乳酸清除率对危重患者预后影响的研究进展  

Research progress on the impact of lactate clearance rate on the prognosis of critically ill patients

作　　者：张秋妍 沈骁 章淬[1] 穆心苇[1] Zhang Qiuyan;Shen Xiao;Zhang Cui;Mu Xinwei(Department of Critical Care Medicine,Nanjing First Hospital,Nanjing Medical University,Nanjing 210006,China)

机构地区：[1]南京医科大学附属南京医院(南京市第一医院)重症医学科,南京210006

出　　处：《中国医师杂志》2023年第8期1255-1259,共5页Journal of Chinese Physician

基　　金：国家自然科学基金(81801891);南京市医学重点科技发展项目(ZKX19021)。

摘　　要：乳酸是机体代谢的主要产物之一,乳酸清除率反映了机体中乳酸的动态变化。近年研究显示,乳酸清除率与脓毒症/脓毒症休克、心源性休克、院外心脏骤停、心血管外科术后及肝肾功能不全等危重患者的预后有关。本文就乳酸的代谢及乳酸清除率在不同危重病患者中的相关研究进展进行综述。Lactic acid is one of the main metabolites in the body,and its clearance rate reflects the dynamic changes of lactic acid in the body.Recent studies have shown that lactate clearance rate is related to the prognosis of critically ill patients with sepsis/septic shock,cardiogenic shock,out-of-hospital cardiac arrest,postoperative cardiovascular surgery,and liver and kidney dysfunction.This article reviews the relevant research progress of lactate metabolism and lactate clearance rate in different critically ill patients.

关 键 词：危重病人医疗 乳酸清除率 预后 

分 类 号：R459.7[医药卫生—急诊医学]