外周血细胞参数对蜜蜂蛰咬后出现器官损伤的预测价值  

Predictive value of peripheral blood cell parameters for the organ injury after bee sting

作　　者：查茜 李清 李倩 郑瑞 冯钢 ZHA Qian;LI Qing;LI Qian;ZHENG Rui;FENG Gang(Department of Clinical Laboratory,the First Affiliated Hospital of Wannan Medical College,Wuhu,Anhui 241001,China;Department of Emergency Medicine,the First Affiliated Hospital of Wannan Medical College,Wuhu,Anhui 241001,China)

机构地区：[1]皖南医学院第一附属医院检验科,安徽芜湖241001 [2]皖南医学院第一附属医院急诊科,安徽芜湖241001

出　　处：《国际检验医学杂志》2023年第17期2134-2137,2143,共5页International Journal of Laboratory Medicine

基　　金：安徽省高校自然科学研究项目(KJ2021ZD0102)。

摘　　要：目的探究蜜蜂蛰咬后外周血细胞参数的变化,评价其对预测器官损伤的价值。方法选取2019年7月至2021年8月在该院急诊科收治的233例蜜蜂蛰咬患者。分别收集患者被蜜蜂蛰咬6 h内外周血细胞参数、临床病理诊断,以及预后情况。使用统计学方法对患者临床实验资料进行分析。结果在收集的233例患者中,有22例(9.4%)发生器官损伤。与无器官损伤的患者相比,蜜蜂蛰咬后出现器官损伤患者白细胞计数、中性粒细胞与淋巴细胞比值、血小板与淋巴细胞比值(PLR)和系统免疫炎症指数(SII)均有所升高,淋巴细胞减少(均P<0.05)。经过Logistic回归分析显示,PLR升高为蜜蜂蛰咬后出现器官损伤的独立危险因素(P<0.05)。经过受试者工作特征曲线分析,PLR预测蜜蜂蛰咬后出现器官损伤的灵敏度为77.3%,特异度为86.3%,阳性预测值为37.0%,阴性预测值为97.3%。结论PLR是蜜蜂蛰咬后出现器官损伤的独立危险因素。蜜蜂蛰咬后PLR较高的患者需要进行积极护理和干预。Objective To investigate the changes in peripheral blood cell parameters after bee sting and to evaluate its value in predicting organ injury after bee sting.Methods From July 2019 to August 2021,a total of 233 bee sting patients treated in Department of Emergency Medicine in the hospital were enrolled in the study.Peripheral blood cell parameters within 6 h after bee sting,clinicopathological diagnosis,and prognosis of the patients were collected,respectively.Patients clinical trial data were analyzed using statistical methods.Results Of the 233 patients,organ injury occurred in 22 cases(9.4%).Compared with bee sting patients without organ damage,patients with organ damage had higher white blood cell count,neutrophil to lymphocyte ratio,platelet to lymphocyte ratio(PLR),and systemic immune inflammation index(SII),and decreased lymphocytes(P<0.05).Logistic regression analysis showed that the increase of PLR was an independent risk factors for organ injury after bee sting(P<0.05).After receiver operating characteristic curve analysis,the sensitivity of PLR in predicting organ injury after bee sting was 77.3%,the specificity was 86.3%,the positive predictive value was 37.0%,and the negative predictive value was 97.3%.Conclusion PLR is an independent risk factor for organ injury after bee sting.Patients with high PLR after bee sting require active care and intervention.

关 键 词：蜜蜂蛰咬 器官损伤 外周血细胞参数 血小板与淋巴细胞比值 

分 类 号：R446.1[医药卫生—诊断学]