肺功能仪器指标及血清指标对BA与COPD的鉴别价值  

The value of pulmonary function instrument to detect pulmonary diffusion function index and serum levels of PGD2,HPx,IL-25 in the differentiation of bronchial asthma and chronic obstructive pulmonary disease

作　　者：刘玲 张春燕 王鑫 Liu Ling;Zhang Chunyan;Wang Xin(Department of Respiratory and Critical Care Medicine,Kaizhou District People's Hospital of Chongqing,Chongqing 405400,China)

机构地区：[1]重庆市开州区人民医院呼吸与危重症医学科,重庆市405400

出　　处：《现代科学仪器》2023年第4期52-55,共4页Modern Scientific Instruments

基　　金：2022年度河北省中医药管理局科研计划项目(2022571)。

摘　　要：目的:分析肺功能仪器指标及血清指标对支气管哮喘(BA)与慢性阻塞性肺疾病(COPD)的鉴别价值。方法:BA患者76例,COPD患者82例,健康体检人群85例。分析血清指标,肺弥散功能指标对其的诊断价值。结果:联合检测前列腺素D2(PGD2)、血红素结合蛋白(HPx)、白细胞介素-25(IL-25)、弥散率(DLco/VA)和一氧化碳弥散(DLco)水平对BA与COPD的鉴别价值最高,曲线下面积(AUC)为0.950,敏感性为88.16%,特异性为90.24%。结论:肺功能仪器指标及血清指标联合检测对BA与COPD的鉴别价值较高。Objective:To analyze the value of pulmonary function instrument and serum index in differentiating bronchial asthma(BA)from chronic obstructive pulmonary disease(COPD).Methods:There were 76 patients with BA,82 patients with COPD and 85 healthy people.The diagnostic value of serum index and pulmonary dispersion function index were analyzed.Results:The combined detection of prostaglandin D2(PGD2),hemopexin(HPx),interleukin-25(IL-25),carbon monoxide lung/alveolar ventilation(DLco/VA)and diffusion capacity for carbon monoxide lung(DLco)levels had the highest value in differentiating BA from COPD,the area under the curve(AUC)was 0.950,and the sensitivity was 88.16%,the specificity was 90.24%.Conclusion:The combined determination of pulmonary function instrument and serum index was of high value in differentiating BA from COPD.

关 键 词：支气管哮喘 慢性阻塞性肺疾病 肺功能仪器 肺弥散功能指标 前列腺素D2 血红素结合蛋白 白细胞介素-25 

分 类 号：R563[医药卫生—呼吸系统]