激素替代疗法治疗围绝经期综合征患者效果及临床指标影响  

Effect of hormone replacement therapy on patients with perimenopausal syndrome and its impact on clinical indicators

作　　者：毛慧琼 Mao Huiqiong(Department of Obstetrics and Gynecology,Suzhou BOE Hospital,Suzhou 215200,China)

机构地区：[1]苏州京东方医院妇产科,江苏苏州215200

出　　处：《实用妇科内分泌电子杂志》2023年第14期78-80,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨围绝经期综合征患者采用激素替代疗法对临床指标的影响。方法选取86例围绝经期综合征患者,采取激素替代疗法进行治疗,对比治疗前后的临床指标。结果患者治疗后卵泡刺激素(FSH)(10.47±5.16)IU/L、促黄体生成素(LH)(11.78±3.13)IU/L水平低于治疗前的(18.45±5.23)IU/L、(16.54±3.25)IU/L,雌二醇(E_(2))(122.38±25.57)pmol/L、孕酮(P)(3.61±0.24)nmol/L水平高于治疗前的(102.56±18.43)pmol/L、(2.68±0.36)nmol/L,差异有统计学意义(P<0.05)。治疗后患者生活质量评分明显高于治疗前,差异有统计学意义(P<0.05)。结论围绝经期综合征患者采取激素替代疗法,能够有效改善患者的激素水平,提高患者生活质量,值得临床推广。Objective To exploretheimpact of hormonereplacement therapy on clinical indicatorsin patientswith perimenopausal syndrome.Methods 86 patients with perimenopausal syndrome were selected and treated with hormone replacement therapy.The clinical indexes before and after treatment were compared.Results The levels of FSH(10.47±5.16)IU/L and luteinizing hormone(LH)(11.78±3.13)IU/L after treatment were lower than those before treatment(18.45±5.23)IU/L and(16.54±3.25)IU/L.The levels of estradiol(E_(2))(122.38±25.57)pmol/L and progesterone(P)(3.61±0.24)nmol/L were higher than those before treatment(102.56±18.43)pmol/L and(2.68±0.36)nmol/L,and the differences were statistically significant(P<0.05).The life quality score of patients after treatment was significantly higher than that before treatment,and the difference was statistically significant(P<0.05).Conclusion Hormone replacement therapy for patients with perimenopausal syndrome can effectively improve their hormone levels and improve their quality of life,which is worthy of clinical promotion.

关 键 词：围绝经期综合征 激素替代疗法 激素水平 

分 类 号：R711.75[医药卫生—妇产科学]