出 处:《中外医学研究》2023年第23期50-53,共4页CHINESE AND FOREIGN MEDICAL RESEARCH
基 金:福建省科技创新平台项目(2020Y2014)。
摘 要:目的:探讨归仲接骨方联合低强度超声治疗胫腓骨骨折术后肝肾亏虚证的临床效果。方法:选取2020年8月-2022年11月在福州市第二医院就诊的106例胫腓骨骨折术后肝肾亏虚证患者。根据随机数表法将其分为治疗组和对照组,各53例。对照组给予低强度超声治疗,治疗组在对照组基础上给予归仲接骨方治疗。比较两组临床疗效,时间指标,治疗前后疼痛程度、相关因子及骨折愈合效果。结果:治疗组总有效率(94.34%)明显高于对照组(81.13%),差异有统计学意义(P<0.05)。治疗组疼痛消失时间、肿胀消失时间、骨痂形成时间均早于对照组,骨折愈合时间短于对照组,差异有统计学意义(P<0.05)。治疗后,两组视觉模拟评分法(VAS)评分均显著降低,治疗组VAS低于对照组,差异有统计学意义(P<0.05)。治疗后,两组血管内皮生长因子(VEGF)水平明显升高,肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)水平明显降低,治疗组VEGF水平高于对照组,TNF-α、CRP水平均低于对照组,差异有统计学意义(P<0.05)。治疗后,治疗组骨痂密度、骨痂量评分均高于对照组,差异有统计学意义(P<0.05)。结论:归仲接骨方联合低强度超声能有效促进胫腓骨骨折愈合,促进骨痂形成,减轻患者疼痛程度。Objective:To investigate the clinical effect of Guizhong Jiegu Prescription combined with low intensity ultrasound in the treatment of postoperative liver and kidney deficiency syndrome of tibia and fibula fractures.Method:A total of 106 patients with postoperative liver and kidney deficiency syndrome of tibia and fibula fractures were selected from the Fuzhou Second Hospital from August 2020 to November 2022.According to random number table method,the patients were divided into treatment group and control group,53 cases in each group.The control group received low intensity ultrasound therapy,and the treatment group was treated with Guizhong Jiegu Prescription on the basis of the control group.The clinical efficacy,time index,pain degree,related factors before and after treatment,and fracture healing effect were compared between the two groups.Result:The total effective rate of treatment group(94.34%)was significantly higher than that of control group(81.13%),and the difference was statistically significant(P<0.05).The time of pain disappearance,swelling disappearance and poroma formation in the treatment group were earlier than those in the control group,and the time of fracture healing was shorter than that in the control group,and the differences were statistically significant(P<0.05).After treatment,the visual analogue scale(VAS)score of both groups were significantly decreased,and the VAS of the treatment group was lower than that of the control group,and the differences were statistically significant(P<0.05).After treatment,vascular endothelial growth factor(VEGF)levels were significantly increased,tumor necrosis factor-α(TNF-α)and C-reactive protein(CRP)levels were significantly decreased,VEGF levels in treatment group was higher than that in control group,and TNF-αand CRP levels were lower than those in control group,and the differences were statistically significant(P<0.05).After treatment,the scores of poroma density and poroma volume in the treatment group were higher than thos e in the control gro
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