云南不明原因猝死病因研究进展  

Research progress on the etiology of Yunnan unexplained sudden death

作　　者：程雪 王跃兵[2] Cheng Xue;Wang Yuebing(School of Public Health,Dali University,Dali 671000,China;Yunnan Institute for Endemic Disease Control and Prevention,Dali 671000,China)

机构地区：[1]大理大学公共卫生学院,大理671000 [2]云南省地方病防治所,大理671000

出　　处：《中华地方病学杂志》2023年第5期426-430,共5页Chinese Journal of Endemiology

基　　金：国家自然科学基金(81960573、81460285);云南省科技厅应用基础研究计划青年项目(2018FD111);徐建国院士工作站项目(2019YS08);云南省地方病防治所青年人才资助培养计划(YIEDC-G202104)。

摘　　要：云南不明原因猝死(云南猝死)多为恶性心律失常引起的心源性猝死,是一种严重威胁病区群众健康的特殊地方病,也是云南省重要的公共卫生问题之一。云南猝死流行病学特点为青壮年高发,民族、家庭和村庄聚集性明显。该病病因至今尚未完全明确,主要病因研究包括毒沟褶菌(小白菌)中毒、肠道病毒感染、遗传性心脏病、克山病病因假说等。在推行以禁食小白菌为主的健康教育,改善病区生产生活条件,加强病区人群健康监测等综合性干预措施后,近年发病率呈明显下降趋势。Yunnan unexplained sudden death is mostly cardiac sudden death caused by malignant arrhythmia,which is a special endemic disease that seriously threatens the health of people in the disease area,and is one of the important public health problems in Yunnan Province.The epidemiological characteristics of Yunnan unexplained sudden death are characterized by a high incidence of young and middle-aged people,and a clear clustering of ethnic groups,families,and villages.The etiology of this disease is not yet fully understood,and the main etiological studies include Trogia venenata poisoning,enterovirus infection,and hereditary heart disease,and hypothesis of the etiology of Keshan disease.After the implementation of comprehensive intervention measures such as health education based on abstinence from Trogia venenata,improving of production and living conditions in the disease area,and strengthening of health monitoring of the population in the disease area,the incidence has shown a significant downward trend in recent years.

关 键 词：猝死 心脏 病因 研究进展 

分 类 号：R541.78[医药卫生—心血管疾病]