丝状真菌杀松材线虫代谢产物研究进展  

Research progress in metabolites of filamentous fungi against Bursaphelenchus xylophilus

作　　者：秦飞飞 杨晓刚 杨立霞 QIN Feifei;YANG Xiaogang;YANG Lixia(College of Life Sciences,Hulunbuir University,Hulunbuir 021008,Inner Mongolia,China)

机构地区：[1]呼伦贝尔学院生命科学学院,内蒙古呼伦贝尔021008

出　　处：《微生物学报》2023年第9期3335-3349,共15页Acta Microbiologica Sinica

基　　金：内蒙古自治区高等学校科学技术研究项目(NJZZ21053);内蒙古自治区自然科学基金(2021BS03029);呼伦贝尔学院博士基金(2020BS10)。

摘　　要：松材线虫病是破坏我国森林生态系统最为严重的病害,具有极强的传播性和破坏性,防治此种病害迫在眉睫。基于对物理和化学方式防治松材线虫的研究,对环境友好度最高的生物防治具有更广的研究前景。丝状真菌及其次级代谢产物,来源于自然,与传统的化学杀线虫药剂相比,对环境影响较小,针对松材线虫的致死作用更为专一,因此,从丝状真菌的次级代谢产物中分离获得杀松材线虫活性产物并测定其结构和活性,对于松材线虫病的防治具有重要意义。本文对丝状真菌产生的具有杀松材线虫活性产物的结构、活性展开综述,发现近二十年共有57个活性产物被发现,且结构多种多样,活性差别较大,为了更好地开展此领域的研究,本文对所有产物的结构和活性进行了系统总结,最后又对该领域的研究进行了总结和展望,以期对松材线虫病的生物防治和丝状真菌杀松材线虫次级代谢产物的深入研究提供参考。Pine wilt disease caused by Bursaphelenchus xylophilus is a severe disease with strong transmission and destructive damage to the forest ecosystems in China.It is therefore urgent to prevent this disease.Compared with the physical and chemical control measures of B.xylophilus,biocontrol being environmentally friendly has a wide research prospect.Filamentous fungi and their secondary metabolites have less impact on the environment and more specific lethal effects on B.xylophilus than chemical nematicides.Therefore,it is of great significance to isolate antinematodal metabolites from filamentous fungi and determine their structures and activities.This paper introduces the structures and activities of metabolites from filamentous fungi against B.xylophilus.A total of 57 metabolites against B.xylophilus have been discovered in the past two decades,with diverse structures and varied activities.This paper systematically summarizes the structures and activities of all the metabolites to facilitate the research in this field and then summarizes and prospects the research in this field.It is hoped that this review will provide reference for the biocontrol of pine wilt disease and the further research on the metabolites of filamentous fungi against B.xylophilus.

关 键 词：松材线虫 丝状真菌 杀松材线虫代谢产物 次级代谢产物结构 次级代谢产物活性 

分 类 号：S763.18[农业科学—森林保护学]