难治性直肠肛周克罗恩病行直肠切除的术式选择和思考  

Surgical option and consideration of proctectomy for refractory anorectal Crohn′s disease

作　　者：陈文豪 丁召[1] Chen Wenhao;Ding Zhao(Department of Colorectal and Anal Surgery,Surgical Center of Inflammatory Bowel Disease,Clinical Center of Intestinal and Colorectal Diseases of Hubei Province,Hubei Key Laboratory of Intestinal and Colorectal Diseases,Quality Control Center of Colorectal and Anal Surgery of Health Commission of Hubei Province,Zhongnan Hospital of Wuhan University,Wuhan 430071,China)

机构地区：[1]武汉大学中南医院结直肠肛门外科、炎症性肠病外科诊疗中心、湖北省肠病医学临床研究中心、肠病湖北省重点实验室、湖北省卫健委结直肠肛门外科专业质量控制中心,武汉430071

出　　处：《中华炎性肠病杂志（中英文）》2023年第3期233-238,共6页Chinese Journal of Inflammatory Bowel Diseases

摘　　要：克罗恩病(CD)是一种病因及发病机制尚不明确的慢性非特异性肠道炎性疾病。CD患者发生肛周病变概率高,肛周病变是CD患者长期不良预后的独立因素。对直肠肛周CD患者需在全面、充分评估疾病的基础上遵循个体化原则进行诊疗。部分难治性直肠肛周CD患者最终需要接受直肠切除(或结直肠切除)以及永久性造口。本文主要围绕难治性直肠肛周CD行直肠切除的术式选择和值得关注和讨论的几个问题展开论述,以期为临床工作提供参考。Crohn′s disease(CD)is a chronic non⁃specific intestinal inflammatory disease with unknown etiology and pathogenesis.CD patients have high probability of developing perianal lesion,which is an independent factor for poor prognosis in CD patients.Diagnosis and treatment of CD patients with rectal and perianal lesions should follow the principle of individualization on the basis of comprehensive assessment.Part of CD patients with refractory rectal and perianal diseases eventually require proctectomy(or proctocolectomy)and permanent stoma.This review mainly focuses on the surgical option and consideration of proctectomy for refractory anorectal Crohn′s disease and key issues worthy of attention and discussion,in order to provide reference for clinical practice.

关 键 词：克罗恩病 肛周病变 直肠切除 术式选择 

分 类 号：R657.1[医药卫生—外科学]