A time sequential microfluid sensor with Tesla valve channels  

作　　者：Pengcheng Zhao Haobin Wang Yaozheng Wang Wei Zhao Mengdi Han Haixia Zhang 

机构地区：[1]National Key Laboratory of Science and Technology on Micro/Nano Fabrication,Beijing Advanced Innovation Center for Integrated Circuits,School of Integrated Circuits,Peking University,Beijing 100871,China [2]Department of Cardiology and Institute of Vascular Medicine,NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides,Key Laboratory of Molecular Cardiovascular Science,Ministry of Education,Beijing Key Laboratory of Cardiovascular Receptors Research,Peking University Third Hospital,Beijing 100191,China [3]Department of Biomedical Engineering College of Future Technology,Peking University,Beijing 100871,China

出　　处：《Nano Research》2023年第9期11667-11673,共7页纳米研究（英文版）

基　　金：supported by the National Key R&D Program of China(No.2018YFA0108100);the National Natural Science Foundation of China(No.62104009);Experiments on human sweat were conducted in accordance with the approved protocol from the institutional review board at Peking University Third Hospital,Beijing,China(No.M2021610).

摘　　要：The concentration of biomarkers in sweat can be used to evaluate human health,making efficient sweat sensing a focus of research.While flow channel design is often used to detect sweat velocity,it is rarely incorporated into the sensing of biomarkers,limiting the richness of sensing results.In this study,we report a time sequential sensing scheme for uric acid in sweat through a sequential design of Tesla valve channels.Graphene electrodes for detecting uric acid and directional Tesla valve flow channels were fabricated using laser engraving technology to realize time sequential sensing.The performance of the channels was verified through simulation.The time sequential detection of uric acid concentration in sweat can help researchers improve the establishment of human health management systems through flexible wearable devices.

关 键 词：time sequential sensing uric acid Tesla valves laser engraving technology 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置]