北京市男男性行为人群对HIV非职业暴露后预防用药的使用意愿及相关因素分析  

Willingness of HIV non-occupational post-exposure prophylaxis and related factors among men who have sex with men in Beijing

作　　者：孙燕鸣[1] 李桂英[1] 卢红艳[1] Sun Yanming;Li Guiying;Lu Hongyan(Institute for HIV/AIDS and STD Prevention and Control,Beijing Center for Disease Prevention and Control,Beijing 100013,China)

机构地区：[1]北京市疾病预防控制中心性病艾滋病防治所,北京100013

出　　处：《中华流行病学杂志》2023年第8期1264-1269,共6页Chinese Journal of Epidemiology

基　　金：北京市科技计划(D171100006717002);北京市疾病预防控制中心/北京市预防医学研究中心科研培育专项(2019-BJYJ-13)。

摘　　要：目的分析MSM对HIV非职业暴露后预防(nPEP)用药的使用意愿及相关因素。方法采用同伴推动抽样法招募MSM进行面对面问卷调查,估算样本量为600人。收集研究对象的社会人口学、行为学、nPEP知晓和使用意愿情况,采用复杂抽样的logistic回归模型分析MSM的nPEP用药相关因素。结果共招募14轮,招募研究对象MSM 608人,年龄(41.6±11.0)岁,MSM的nPEP知晓率为55.4%(95%CI:49.4%~59.4%),nPEP用药既往使用率为4.5%(95%CI:2.9%~6.2%),有使用意愿的占35.9%(95%CI:31.1%~40.7%)。在无使用意愿的原因中,不知晓nPEP的占68.9%(244/354),认为不会感染的侥幸心理占24.6%(87/354)。logistic多因素分析结果显示,MSM的nPEP用药使用意愿的相关因素包括25~39岁年龄组(aOR=1.80,95%CI:1.01~3.20)、艾滋病知识知晓者(aOR=2.43,95%CI:1.52~3.90)、最近半年每次肛交使用安全套(aOR=1.76,95%CI:1.11~2.79)。结论北京市MSM中nPEP用药既往使用率较低,使用意愿也有待提高,应加强对MSM社会组织的培训,提高同伴教育在nPEP用药推广方面的作用。Objective To examine the willingness of HIV non-occupational post-exposure prophylaxis(nPEP)among MSM and factors related were also assessed.Methods The respondent-driven sampling method was used to recruit MSM for a face-to-face interview with a structured questionnaire,the sample size was estimated at 600 subjects.Demographic data,sexual behavior,awareness,and willingness regarding nPEP were collected.The factors related to willingness to nPEP were assessed using complex logistic regression.Results A total of 14 rounds were recruited and 608 MSM subjects were included in the study.The average age was(41.6±11.0)years.55.4%(95%CI:49.4%-59.4%)were aware of nPEP,and 4.5%(95%CI:2.9%-6.2%)have used its.35.9%(95%CI:31.1%-40.7%)expressed interest in taking nPEP if needed.Among the reasons for not being willing to take nPEP,68.9%(244/354)were never heard of nPEP,and 24.6%(87/354)were a fluke mentality.The multivariate logistic analysis results showed that the willingness of nPEP awareness of MSM was related to the group aged 25-39 years old(aOR=1.80,95%CI:1.01-3.20),knowing a group of HIV prevention knowledge(aOR=2.43,95%CI:1.52-3.90),group of consistent condom use in anal sex in the past half of year(aOR=1.76,95%CI:1.11-2.79).Conclusions The use rate of nPEP among MSM in Beijing was low,and the willingness to use in the future also needs to be improved.The training of social organizations should be strengthened to improve the role of peer education in promoting nPEP.

关 键 词：艾滋病病毒 男男性行为人群 非职业暴露后预防 相关因素 

分 类 号：R512.91[医药卫生—内科学]