CT模拟定位机在调强放疗位置验证中的应用  

Application of CT Simulator in Position Verification of Intensity Modulated Radiotherapy

作　　者：齐洪志[1] 杨玉刚[1] 郝洁[1] 许林[1] 尚革[1] QI Hongzhi;YANG Yugang;HAO Jie;XU Lin;SHANG Ge(Cancer Center,The First Affiliated Hospital of Xinjiang Medical University,Urumqi Xinjiang 830054,China)

机构地区：[1]新疆医科大学第一附属医院肿瘤中心,新疆乌鲁木齐830054

出　　处：《中国医疗设备》2023年第9期53-58,共6页China Medical Devices

基　　金：国家自然科学基金(81860360)。

摘　　要：目的 探讨CT模拟定位机在调强放疗位置验证中的应用。方法 选取新疆医科大学第一附属医院准备实施调强放射治疗患者60例,使用CT模拟定位机对其放疗位置进行验证,并将患者随机分配至瓦里安和医科达加速器,分别使用电子射野影像系统(Electronic Portal Imaging Device,EPID)和锥形束CT(Cone Beam Computed Tomography,CBCT)重新进行位置验证,分析位置验证结果。结果 使用CT模拟定位机位置验证在左右(Lateral,Lat)、前后(Vertical,Vrt)和头脚(Longitudinal,Lng)3个方向的位置偏差分别为(1.5333±0.6456)、(1.2600±0.5063)、(1.0333±0.3676)mm。在Lat方向和Vrt方向上,EPID和CBCT位置验证结果与CT模拟机位置验证比较,差异均无统计学意义(P>0.05)。在Lng方向,CT模拟定位机平均位移显著小于EPID和CBCT(P<0.05)。结论 使用CT模拟定位机可以获取软组织分辨率更好的位置验证影像,方便医生观察靶区和危及器官的相对关系,可以很好地完成放疗前位置验证。Objective To explore the application of CT simulator in the position verification of intensity modulated radiotherapy.Methods Sixty patients with volumetric modulated arc therapy in the First Affiliated Hospital of Xinjiang Medical University were selected.The radiotherapy position was verified by CT simulator,and the patients were randomly assigned to Varian and Elekta accelerators.The position was retested by electronic portal imaging device(EPID)and cone beam CT(CBCT)respectively,and the position verification results were analyzed.Results The position deviation of CT simulator in lateral(Lat),vertical(Vrt)and longitudinal(Lng)directions were(1.5333±0.6456),(1.2600±0.5063),(1.0333±0.3676)mm respectively.In Lat direction and Vrt direction,there was no significant difference between EPID and CBCT position verification results and CT simulator position verification results(P>0.05).In the Lng direction,the average displacement of CT simulator was significantly lower than EPID and CBCT(P<0.05).Conclusion Using CT simulator can obtain position verification images with better soft tissue resolution,which is convenient for doctors to observe the relative relationship between target and organs at risk,the position verification before radiotherapy can be well completed.

关 键 词：电子射野影像系统 锥形束CT CT模拟定位机 位置验证 

分 类 号：R144[医药卫生—公共卫生与预防医学] R815.6