晚期非小细胞肺癌间接经济负担及其影响因素分析  

Indirect Economic Burden and Its Influencing Factors of Patients with Advanced Non-Small Cell Lung Cancer

作　　者：夏宇 陈英耀[1,2] 杨毅[1,2] Xia Yu;Chen Yingyao;Yang Yi(School of Public Health,Fudan University,Shanghai,200032,China;NHC Key Laboratory of HealthTechnology Assessment(Fudan University),Shanghai,200032,China;不详)

机构地区：[1]复旦大学公共卫生学院,上海200032 [2]国家卫生健康委员会卫生技术评估重点实验室(复旦大学),上海200032

出　　处：《中国卫生经济》2023年第8期70-73,77,共5页Chinese Health Economics

基　　金：美国中华医学基金会《中国卫生技术评估示范项目》(19-318)。

摘　　要：目的:测算我国晚期非小细胞肺癌(non-small cell lung cancer,NSCLC)患者自疾病确诊以来的疾病间接经济负担及其影响因素。方法:采用方便抽样与整群抽样相结合的方式,于2020年11月—2021年6月对上海市、江苏省、福建省、山东省和四川省13家三级公立医院的晚期NSCLC患者及其照护者进行问卷调查,匡算晚期NSCLC相关间接费用,并利用广义线性回归模型探明其影响因素。结果:研究共纳入患者及其照护者603对。自疾病确诊以来,晚期NSCLC患者例均疾病间接费用为7842.24元。广义线性回归结果显示,照护者的年龄、文化程度、职业类型、担任照护者时长、患者病程和疾病进展情况是晚期NSCLC间接经济负担的影响因素。结论:晚期NSCLC间接经济负担不可忽视,建议持续提高癌症整体诊疗水平,提高有效治疗的可及性,改善患者生存率和生命质量。统筹考虑患者人群特征,采取针对性预防策略来缓解疾病间接经济负担;提供多渠道经济补助,减轻疾病经济负担。Objective:To estimate the indirect cost of locally advanced and metastatic non-small cell lung cancer(NSCLC)since diagnosis in China and explore the predictors.Methods:Based on a combination of convenience sampling and cluster sampling,data was obtained from patients with advanced NSCLC(stage IIIB~IV)and their caregivers in 13 hospitals in Shanghai,Jiangsu,Fujian,Shandong and Sichuan Province from November 2020 to June 2021.The indirect costs of the disease since diagnosis were calculated.The generalized linear model(GLM)was used to explore the influencing factors.Results:A total of 603 pairs of patients and pa-tient-caregivers participated in this investigation.The indirect medical cost on advanced NSCLC since the patient diagnosed was 7842.24 yuan per capita.The GLM results showed that the indirect medical cost was significantly influenced by caregivers’age,educa-tional attainment,occupation type,caregiving duration,duration of disease since diagnosis and disease progression.Conclusion:The indirect economic burden related to advanced NSCLC in China is considerable on patients.To minimize the indirect economic burden,it is recommended to improve the cancer treatment level,strengthen the accessibility for more effective therapies,improve the survival rate and quality of life of patients,and consider the characteristics of the patient in an integrated manner in order to target prevention and alleviate the indirect economic burden of disease.

关 键 词：晚期非小细胞肺癌 间接经济负担 影响因素 

分 类 号：R1-9[医药卫生—公共卫生与预防医学] F224.5[经济管理—国民经济]