温阳通络法组方汤剂联合雷火灸治疗阳虚血瘀型DPN的临床效果  

Clinical effect of Wenyang Tongluo method prescription decoction combined with thunder-fire moxibustion in the treatment of DPN with Yang deficiency and blood stasis type

作　　者：郭浩楠 王可可 张彦芬 吴红群 徐彦娜 GUO Haonan;WANG Keke;ZHANG Yanfen;WU Hongqun;XU Yanna(Integrated Traditional and Western Medicine Department,Shangluo Central Hospital,Shangluo 726000,China)

机构地区：[1]商洛市中心医院中西医结合科,陕西商洛726000

出　　处：《临床医学研究与实践》2023年第25期138-141,共4页Clinical Research and Practice

摘　　要：目的探讨温阳通络法组方汤剂联合雷火灸治疗阳虚血瘀型糖尿病周围神经病变(DPN)的临床效果。方法选取2019年5月至2021年5月我院110例阳虚血瘀型DPN患者,按照随机数字表法将其分为对照组和观察组,各55例。对照组接受西医常规治疗,观察组接受温阳通络法组方汤剂联合雷火灸治疗。比较两组的治疗效果。结果治疗2周后,观察组的主症及次症积分均低于对照组(P<0.05)。治疗2周后,观察组右下肢腓总神经、胫神经的感觉神经传导速度(SNCV)及运动神经传导速度(MNCV)均高于对照组(P<0.05)。治疗2周后,观察组的超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、总抗氧化能力(T-AOC)水平均高于对照组,丙二醛(MDA)、γ-谷氨酰转肽酶(GGT)水平均低于对照组(P<0.05)。观察组的治疗总有效率高于对照组(P<0.05)。结论温阳通络法组方汤剂联合雷火灸治疗阳虚血瘀型DPN的临床效果较好。Objective To explore the clinical effect of Wenyang Tongluo method prescription decoction combined with thunder-fire moxibustion in the treatment of diabetic peripheral neuropathy(DPN)with Yang deficiency and blood stasis type.Methods A total of 110 DPN patients with Yang deficiency and blood stasis type in our hospital from May 2019 to May 2021 were selected and divided into control group and observation group according to the random number table method,with 55 cases in each group.The control group received conventional western medicine treatment,and the observation group received Wenyang Tongluo method prescription decoction combined with thunder-fire moxibustion treatment.The therapeutic effects of the two groups were compared.Results After 2 weeks of treatment,the scores of main symptoms and secondary symptoms in the observation group were lower than those in the control group(P<0.05).After 2 weeks of treatment,the sensory nerve conduction velocity(SNCV)and motor nerve conduction velocity(MNCV)of the common peroneal nerve and tibial nerve of the right lower extremity in the observation group were higher than those in the control group(P<0.05).After 2 weeks of treatment,the levels of superoxide dismutase(SOD),glutathione peroxidase(GSH-Px)and total antioxidant capacity(T-AOC)in the observation group were higher than those in the control group,while the levels of malondialdehyde(MDA)and gamma glutamyl transpeptidase(GGT)were lower than those in the control group(P<0.05).The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).Conclusion Wenyang Tongluo method prescription decoction combined with thunder-fire moxibustion in the treatment of DPN with Yang deficiency and blood stasis type has a better clinical effect.

关 键 词：糖尿病周围神经病变 阳虚血瘀型 温阳通络法 雷火灸 

分 类 号：R259[医药卫生—中西医结合]