某儿童医院2020年儿科处方对照药品说明书用药情况分析  

Analysis of children′s medication in pediatric prescriptions of a children′s hospital in 2020

作　　者：杨文辉[1] 范程程 张双 朱俊霞 姚亚飞 Yang Wenhui;Fan Chengcheng;Zhang Shuang;Zhu Junxia;Yao Yafei(Department of Pharmacy,Third Affiliated Hospital of Zhengzhou University,Zhengzhou Henan 450052,China;Department of Pharmacy,Henan NO.3 Provincial People′s Hospital,Zhengzhou Henan 450001,China)

机构地区：[1]郑州大学第三附属医院药学部,河南郑州450052 [2]河南省省直第三人民医院药学部,河南郑州450001

出　　处：《中国药物与临床》2023年第2期120-124,共5页Chinese Remedies & Clinics

摘　　要：目的以某三甲儿童医院2020年全年儿科处方分析儿童用药的现状。方法抽取某医院全年的192774张儿科处方,将全部药品汇总后逐一核对药品说明书信息,将用法用量、儿童用药、儿童药代动力学、儿童用药、注意事项等信息进行汇总,并根据药品的药理属性、剂型及使用频率进行分类分析。结果儿科处方中312种药品,儿童适宜使用药品占73.1%(228/312),剂型上注射剂品种数最多,占22.1%(69/312),对用法用量的标注也较完备87.0%(60/69)。抗感染药物的新生儿用法用量、儿童药代动力学标注率相对较高,分别占18.2%(4/22)和31.8%(7/22)。全年儿科处方中口服液使用频率最高36.92%(18473/500345);按药理属性中成药使用频率最高,占35.41%(177173/500345),但儿童适宜使用比例仅为52.33%(92715/177173)。儿科处方药品使用相对集中,使用频率占70%时药品数量不足50种。结论此三甲儿童医院儿科处方选用的药品中,儿童适宜使用药品占比较大,但儿童专用药品仍较少,药品说明书完整性需进一步提高。Objective To analyze the current situation of pediatric medication in a third-grade class-A children′s hospital for the whole year of 2020.Methods A total of 192774 pediatric prescriptions were selected from a hospital for the whole year,all drugs were summarized and the information of drug instruction was checked one by one.The information of usage and dosage,drug use for children,pharmacokinetics for children,drug use for children,precautions and other information were summarized,and classified and analyzed according to the pharmacological properties,the dosage forms and the frequency of use.Results Among 312 drugs in pediatric prescriptions,73.1%(228/312)were suitable for children,the number of injection types was the most,and the la-beling of usage and dosage was relatively complete(87.0%,60/69).In terms of pharmacological properties,the us-age and dosage of anti-infective drugs in neonates and pharmacokinetic labeling rates in children were relatively high,but only 18.2%(4/22)and 31.8%(7/22).Oral liquid was the most frequently used in pediatric prescriptions for 36.92%(18473/500345)of the year.According to the pharmacological properties,Chinese patent medicines were the most frequently used,accounting for 35.41%(177173/500345),but the proportion of suitable use for children was only 52.33%(92715/177713).The use of pediatric prescription drugs was relatively concentrated,and the number of drugs was less than 50 when the use frequency accounted for 70%.Conclusion The propor-tion of drugs suitable for children in the pediatric prescriptions in third-grade class-A children′s hospital is rela-tively large,but there are still relatively few specialized drugs for children,and the integrity of drug instructions needs to be further improved.

关 键 词：药物处方 儿童 药品 说明书 

分 类 号：R95[医药卫生—药学]