吉林市献血者HTLV感染情况分析  

Analysis of HTLV Infection among Blood Donors in Jilin City

作　　者：赵宇[1] 黄建鹏 ZHAO Yu;HUANG Jianpeng(Jilin City Red Cross Center Blood Station,Jilin,Jilin 132000)

机构地区：[1]吉林市红十字中心血站,吉林吉林132000

出　　处：《智慧健康》2023年第16期36-39,共4页Smart Healthcare

摘　　要：目的调查吉林市2016-2022年无偿献血者人类嗜T淋巴细胞病毒(HTLV-Ⅰ/Ⅱ)感染情况,为本地区血液筛查策略的制定提供依据,从而更好地保障血液安全。方法采用酶联免疫吸附试验(ELISA)对吉林市2016-2020年265529份无偿献血者血液标本进行HTLV-Ⅰ/Ⅱ抗体筛查,检测出的阳性标本送国家卫生健康委员会临床检验中心,采取蛋白印迹法和聚合酶链式反应荧光探针法进一步确认。结果初筛阳性献血者25例(0.09‰),其中确认阳性6例(0.02‰),不确定1例(0.003‰),职业均为县级市农民。结论吉林市总体HTLV流行率低,可对吉林市城区外的县级市献血者实施筛查。Objective To investigate infection status of human T-lymphotropic virus(HTLV-Ⅰ/Ⅱ)among unpaid blood donors in Jilin City from 2016 to 2022,to provide a basis for development of blood screening strategies in the area and ensure blood safety.Methods The paper screened 265529 blood samples from unpaid blood donors in Jilin City from 2016 to 2020 for HTLV-Ⅰ/Ⅱantibody by ELISA.Positive samples were sent to clinical Test Center of the National Health Commission and further confirmed by protein blot and polymerase chain reaction fluorescent probe.Results 25 cases(0.09‰)of positive blood donors were initially screened,of which 6 cases(0.02‰)were confirmed positive and 1 case was uncertain(0.003‰).All of them were farmers in county-level city.Conclusion Overall prevalence of HTLV in Jilin is low and blood donors in county-level city outside urban area of Jilin can be screened.

关 键 词：人类嗜T淋巴细胞病毒 酶联免疫吸附试验 无偿献血者 

分 类 号：R446.6[医药卫生—诊断学] R457.1[医药卫生—临床医学]