奥硝唑片联合新生化颗粒预防高危感染因素人工流产术后的疗效对比分析  

Analysis of the Efficacy of Ornidazole Tablets Combined with Xinshenghua Granules in Preventing High-Risk Infectious Factors after Induced Abortion

作　　者：宁俊红 陶莲英 蔡良音 NING Jun-hong;TAO Lian-ying;CAI Liang-yin(Department of Pharmacy,Shanghai Baijia Maternity Hospital,Shanghai 201102,China;Department of Obstetrics and Gynecology,Shanghai Baijia Maternity Hosp ital,Sh anghai 201102,China;Department of Pharmacy,Wusong Branch of Zhongshan Hospital Affiliated to Fudan University,Shanghai 200940,China)

机构地区：[1]上海百佳妇产医院药剂科,上海201102 [2]上海百佳妇产医院妇产科,上海201102 [3]复旦大学附属中山医院吴淞医院药剂科,上海200940

出　　处：《中国合理用药探索》2023年第8期84-87,共4页Chinese Journal of Rational Drug Use

基　　金：上海市闵行区卫生和计划生育委员会科研基金(2018MW64)。

摘　　要：目的:探讨并比较奥硝唑片联合新生化颗粒预防高危感因素人工流产术后疗效差异。方法:回顾性选取某院2021年1~12月期间收治的有高危感染因素人工流产患者100例,按照给药方案分为对照组和观察组,每组50例。对照组给予盐酸多西环素肠溶胶囊联合新生化颗粒,观察组给予奥硝唑片联合新生化颗粒。观察两组患者术后1周的阴道异常出血、阴道分泌物恶臭、宫体压痛、发热、白细胞计数升高、C反应蛋白升高等情况,比较两组患者术后1周阴道血流和宫腔残留物情况。结果:术后1周内,观察组阴道异常出血、阴道分泌物恶臭、宫体压痛、发热的总发生率(2.00%)低于对照组(10.00%,P<0.05);观察组患者白细胞计数、C反应蛋白升高(2.00%)少于对照组(10.00%,P<0.05);观察组患者出现阴道血流和宫腔残留物者少于对照组,但两组比较无统计学差异(P>0.05)。结论:奥硝唑片联合新生化颗粒预防高危感染因素的人工流产术后效果优于盐酸多西环素肠溶胶囊联合新生化颗粒。Objective:To explore and compare the effect of ornidazole combined with Xinshenghua granules in preventing infections in patients at high risks after induced abortion.Methods:One hundred patients at high risks for infections after induced abortion admitted to a hospital from January 2021 to December 2021 were retrospectively selected and divided into the control group and observation group according to the dosing regimen,with 50 patients in each group.The control group was treated with doxycycline hyclate enteric-coated capsules combined with Xinshenghua granules,and the observation group was treated with ornidazole tablets combined with Xinshenghua granules.The hemorrhage from vagina,malodorous vaginal discharge,tenderness of body of uterus,fever,increased white blood cells and increased C-reactive proteins were observed during 1 week after the operation in two groups,and the vaginal blood flow and intrauterine residues were compared in two groups after 1 week of the operation.Results:In the first week after the operation,the total incidence of hemorrhage from vagina,malodorous vaginal discharge,tenderness of body of uterus and fever in the observation group(2.00%)was lower than that in the control group(10.00%,P<0.05).The proportion of patients with increased white blood cells and increased C-reactive proteins in the observation group(2.00%)was lower than that in the control group(10.00%,P<0.05).The number of patients with vaginal blood flow and intrauterine residues in the observation group was decreased than that in the control group,without significant statistical difference between the two groups(P>0.05).Conclusion:Ornidazole combined with Xinshenghua granules has superior prophylactic effect in patients with high risks for infections after induced abortion,compared with doxycycline hyclate enteric-coated capsules combined with Xinshenghua granules.

关 键 词：奥硝唑 新生化颗粒 高危感染因素 人工流产术后 预防 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]