Synthesis and Insecticidal Evaluation of Novel Phthalic Diamides Containing 1,2,3-Triazoles via Click Reaction  

作　　者：Yinbo Chen Youxin Xiao Xusheng Shao Xiaoyong Xu Zhong Li 

机构地区：[1]Shanghai Key Laboratory of Chemical Biology,School of Pharmacy,East China University of Science and Technology,Shanghai 200237,China

出　　处：《Chinese Journal of Chemistry》2014年第7期592-598,共7页中国化学（英文版）

基　　金：This work was financially supported by the National Basic Research Program of China(973 Program,No.2010CB126100);the National High Technology Research and Development Program of China(863 Program Program,No.2011AA10A207);the National Natural Science Foundation of China(Nos.21372079;21272071);This work was also partly supported by the National Key Technology R&D Program of China(No.2011BAE06B01)and the Fundamental Research Funds for the Central Universities.

摘　　要：A series of novel phthalic diamide derivatives containing 1,2,3-triazole moiety were synthesized using one-pot click chemistry approach and characterized by ^(1)H NMR and HRMS.The insecticidal activity against armyworm(Mythimna separata),Tetranychus cinnabarinus and cowpea aphid(Aphis craccivora)was evaluated.Compounds 4Ⅱ-a and 4Ⅱ-i showed 50%insecticidal activity against armyworm(Mythimna separata)at the concentration of 4 mg/L and one-third of the compounds had moderate activity against Tetranychus cinnabarinus at 500 mg/L.

关 键 词：phthalic diamide 1 2 3-TRIAZOLE click chemistry SYNTHESIS bioactivity 

分 类 号：O62[理学—有机化学]