Platinum-Catalyzed Asymmetric Ring-opening Reaction of Oxabenzonorbornadiene with Terminal Alkynes  

作　　者：Yuhua Long Han Jiang Zhifu Zou Kaixuan Chen Yali Fang 

机构地区：[1]School of Chemistry and Environment,South China Normal University,Guangzhou,Guangdong 510006,China

出　　处：《Chinese Journal of Chemistry》2014年第7期613-618,共6页中国化学（英文版）

基　　金：the National Natural Science Foundation of China(No.41376149);the Guangzhou Pearl River New Star Plan of Science and Technology Program(No.2012J2200015).

摘　　要：A novel platinum-catalyzed asymmetric ring-opening reaction of oxabenzonorbornadiene with terminal alkynes is described.The reaction affords optically active cis-2-alkynyl-1,2-dihydronaphthalen-1-ols in moderate yields with good enantioselectivity in the presence of catalytic amounts of Pt(COD)Cl_(2)/(S)-BINAP and an excess of zinc powder.The products were obtained exclusively with the relative cis-configuration of the ring substituents and the prevalent(1R,2S)-configuration of the stereocenters,as determined by single crystal X-ray diffraction analysis.

关 键 词：platinum-catalyzed asymmetric catalysis ring-opening reaction oxabenzonorbornadiene terminal alkyne 

分 类 号：O62[理学—有机化学]