N-Heterocyclic Carbene-catalyzed Reactions of o-Aminonitriles with Carbonyl Compounds Approach to 2,3-Dihydroquinazolin-4(1H)-ones  

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作  者:Hongxin Chai Jiarong Li Liupan Yang Mingxing Liu Deli Yang Qi Zhang Daxin Shi 

机构地区:[1]School of Chemical Engineering and Environment,Beijing Institute of Technology,Beijing 100081,China [2]Jiangsu Hengrui Medicine Co.,Ltd.,No.7 Kunlunshan Road,Lianyungang Eco&Tech Development Zone,Lianyungang,Jiangsu 222047,China

出  处:《Chinese Journal of Chemistry》2014年第9期865-870,共6页中国化学(英文版)

基  金:Financial support from the International S&T Cooperation Program of China(No.2012DFR40240)is gratefully acknowledged.

摘  要:A green,efficient and convenient N-heterocyclic carbene-catalyzed procedure for the synthesis of novel 2,3-dihydroquinazolin-4(1H)-one derivates via condensation of o-aminonitriles and various carbonyl compounds was described.

关 键 词:quinazolin-4(1H)-one N-heterocyclic carbene CARBONYL o-aminonitrile fused pyrimidinone 

分 类 号:O62[理学—有机化学]

 

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