Fc-PIP Catalyzed Asymmetric Synthesis of cis-2,3-Dihydrobenzofurans  

作　　者：Shanshan Jiang Bin Hu Xingxin Yu Weiping Deng 

机构地区：[1]Shanghai Key Laboratory of New Drug Design,School of Pharmacy,East China University of Science and Technology,Shanghai 200237,China

出　　处：《Chinese Journal of Chemistry》2014年第8期694-698,共5页中国化学（英文版）

基　　金：The authors are grateful to the Fundamental Research Funds for the Central Universities,the National Natural Science Foundation of China(No.21372074).

摘　　要：A highly enantioselective intramolecular Michael addition-Lactonization domino reaction of a range of enon acids catalyzed by nuleophilic organocatalyst(Fc-PIP)was developed,furnishing cis-2,3-dihydrobenzofuran derivatives with excellent enantioselecitivities(94%-98%ee)and good diastereoselectivities(up to 99/1).

关 键 词：Michael addition-Lactonization DIHYDROBENZOFURAN Fc-PIP 

分 类 号：O62[理学—有机化学]