禽白血病病毒与多种病原协同致病机理研究进展  

Research Progress on Synergistic Pathogenesis of Avian Leukosis Virus and Multiple Pathogens

作　　者：曾熙雯 温贵兰[1] 田兴舟 ZENG Xiwen;WEN Guilan;TIAN Xingzhou(College of Veterinary Medicine,Guizhou University,Guiyang,Guizhou 550025;Engineering Technology Research Center for Animal Biologics,Guiyang,Guizhou 550016)

机构地区：[1]贵州大学动物科学学院,贵州贵阳550025 [2]贵州省动物生物制品工程技术研究中心,贵州贵阳550016

出　　处：《中国家禽》2023年第9期74-81,共8页China Poultry

基　　金：2021年度贵州省科技支撑计划项目(黔科合支撑[2021]一般164);2020年度贵州省地方家禽产业联合攻关项目(黔财农[2020]175);2020年贵州省高等学校教学内容和课程体系改革项目(GZJG20200035)。

摘　　要：禽白血病(Avian leukosis,AL)是一类由禽白血病病毒(Avian leukosis virus,ALV)引起的禽类肿瘤性传染病。近年来,除ALV不同亚群的感染被报道以外,ALV也常被发现与其他病原共同感染,发病机制尚不明确,每年给家禽养殖行业造成严重的经济损失。文章对ALV的基因组特征、复制特点、基本致病机理、与其他禽类免疫抑制性病毒、细菌和寄生虫等病原的协同致病机理等进行了综述,为AL的防控提供更具有针对性的指导意见。Avian leukosis(AL)is a kind of avian tumor infectious disease caused by avian leukosis virus(ALV).In recent years,in addition to the reported infection of different subgroups of ALV,ALV is often found to be co-infected with other pathogens,and the pathogenesis of which is not clear,causing serious economic losses to the poultry industry every year.This paper reviewed the genomic characteristics,replication characteristics,basic pathogenic mechanism and synergistic pathogenic mechanism of ALV with other avian immunosuppressive viruses,bacteria and parasites to provide more targeted guidance for prevention and control of AL.

关 键 词：禽白血病病毒 致病机制 协同致病 

分 类 号：S855.3[农业科学—临床兽医学]