AP2/ERF转录因子参与植物次生代谢和逆境胁迫响应的研究进展  

Research Progress of AP2/ERF Transcription Factors Participating in Plant Secondary Metabolism and Stress Response

作　　者：兰孟焦 后猛[1] 肖满秋[2] 李臣 潘皓 张允刚[1] 卢凌志[2] 侯隆英 葛瑞华[2] 吴问胜 李强[1] LAN Mengjiao;KOU Meng;XIAO Manqiu;LI Chen;PAN Hao;ZHANG Yungang;LU Lingzhi;HOU Longying;GE Ruihua;WU Wensheng;LI Qiang(Xuzhou Institute of Agricultural Sciences in Xuhuai District of Jiangsu Province/Key Laboratory of Sweetpotato Biology and Genetic Breeding,Ministry of Agriculture and Rural Affairs,Xuzhou 221131;Crop Institute of Jiangxi Academy of Agricultural Sciences,Nanchang 330200)

机构地区：[1]江苏徐淮地区徐州农业科学研究所/农业农村部甘薯生物学与遗传育种重点实验室,徐州221131 [2]江西省农业科学院作物研究所,南昌330200

出　　处：《植物遗传资源学报》2023年第5期1223-1235,共13页Journal of Plant Genetic Resources

基　　金：国家甘薯产业技术体系(CARS-10);江西薯芋类作物良种联合攻关(9021109126)。

摘　　要：AP2/ERF(APETALA2/ethylene-responsive factor)是植物中最大的转录因子家族之一,至少含有1个由60~70个高度保守的氨基酸组成的特有的AP2结构域,根据AP2结构域数量和相似性可划分为5个亚家族:AP2(APETALA2)、DREB(Dehydration-responsive element binding proteins)、ERF(Ethylene-responsive factor)、RAV(Related to AB13/VP)和Soloist。AP2/ERF转录因子通过AP2结构域中的YRG和RAYD保守元件与靶基因结合,实现对相关基因的转录调控功能。目前,AP2/ERF已成为研究植物抗逆机制和活性成分生物合成的热点候选基因,越来越多植物AP2/ERF家族及其成员被报道。本研究对近年来有关AP2/ERF家族的最新研究成果进行了总结,综述了AP2/ERF家族转录因子的结构特征与分类,重点介绍了该类转录因子调控植物次生代谢产物的合成以及参与生物、非生物胁迫应答等方面的研究进展,并展望了AP2/ERF转录因子可能的研究热点和领域,以期为今后进一步挖掘和利用该类转录因子基因进行植物遗传改良以及种质创新提供参考。AP2/ERF(APETALA2/ethylene responsive factor)is one of the largest transcription factor(TF)families in plants,which contains at least one specific AP2 domains composed of 60-70 highly conserved amino acids.Depending on the number and sequence similarity of AP2 domains,this family can be classified into five subfamilies:AP2(APETALA2),DREB(dehydration-responsive element binding proteins),ERF(ethyleneresponsive factor),RAV(related to AB13/VP),and Soloist.AP2/ERF TFs regulate their expression by binding to target genes through YRG and RAYD conserved elements in the AP2 domain.At present,AP2/ERF TFs have become a hot candidate gene for studying plant stress resistance mechanisms and biosynthesis of active ingredients.More and more AP2/ERF families and their members have been reported.In this review,we summarized the latest research achievements on plant AP2/ERF family,including the structural characteristics and classification,and the research progress of AP2/ERF TFs involved in regulation of plant secondary metabolites synthesis,participation in biological and abiotic stress response was mainly introduced.Meanwhile,possible hot research topics and fields of AP2/ERF were proposed,which may provide a reference for further mining and utilization of such transcription factor genes for plant genetic improvement and germplasm innovation.

关 键 词：AP2/ERF 转录调控 次生代谢 生物及非生物胁迫 

分 类 号：Q943.2[生物学—植物学]