桥本甲状腺炎患者日常饮食及生活习惯调查分析  

Investigation and analysis of daily diet and living habits of Hashimoto's thyroiditis patients

作　　者：郭喜 韩吉华 毕文 聂春磊[1] Guo Xi;Han Jihua;Bi Wen;Nie Chunlei(Thyroid Ward,Department of Head and Neck Surgery,Cancer Hospital Affiliated to Harbin Medical University,Harbin 150081,China)

机构地区：[1]哈尔滨医科大学附属肿瘤医院头颈外科甲状腺病房,哈尔滨150081

出　　处：《中华地方病学杂志》2023年第8期647-651,共5页Chinese Journal of Endemiology

摘　　要：目的了解桥本甲状腺炎(HT)患者日常饮食及生活习惯,探讨HT发病的影响因素。方法选取2021年3-12月于哈尔滨医科大学附属肿瘤医院甲状腺外科门诊就诊人群作为调查对象,分为观察组(HT患者,106例)和对照组(健康人群,63例)。采用调查问卷收集两组人群日常饮食及生活习惯信息,体格检查收集身高、体重等信息,全自动化学发光免疫分析仪检测血清甲状腺功能指标促甲状腺激素(TSH)、游离三碘甲状腺原氨酸(FT3)和游离甲状腺素(FT4)水平,并进行两组间比较与分析;采用多因素logistic回归分析HT发病的影响因素。结果单因素分析结果显示,两组间性别比例、血清TSH水平比较差异均有统计学意义(均P<0.05);观察组睡眠时长<6 h/d、经常看手机、每周吃油炸食品≥1次及每周吃肉量≥1 kg的人数构成比均高于对照组,而每周喝茶≥1次、每周抽烟≥1次、日常口味偏咸、每周吃坚果≥1次及每周吃蔬菜量≥1 kg的人数构成比均低于对照组,差异均有统计学意义(均P<0.05)。多因素logistic回归分析结果显示,女性、睡眠时长<6 h/d、每周吃肉量≥1 kg、血清TSH水平升高是HT发病的危险因素[比值比(OR)=3.37、4.11、2.48、1.14,95%置信区间(CI):1.08~10.55、1.46~11.59、1.00~6.51、1.00~1.30];而每周吃蔬菜量≥1 kg是HT发病的保护因素(OR=0.36,95%CI:0.17~0.79)。结论女性、不良的饮食与生活习惯是HT发病的危险因素。Objective To investigate the daily diet and living habits of Hashimoto's thyroiditis(HT)patients,and to explore the influencing factors of HT.Methods The patients admitted to the Thyroid Surgery Clinic of Cancer Hospital Affiliated to Harbin Medical University from March to December 2021 were selected as the investigation subjects and were divided into observation group(106 patients with HT)and control group(63 healthy people).Questionnaire was used to collect the information of daily diet and living habits of the two groups,and physical examination was used to collect the information of height and weight.The levels of serum thyroid function indicators thyroid stimulating hormone(TSH),free triiodothyronine(FT3)and free thyroxin(FT4)were tested by automatic chemiluminescence immunoassay,and the comparison and analysis were conducted between the two groups.Multivariate logistic regression was used to analyze the influencing factors of HT.Results The results of univariate analysis showed that there were significant differences in sex ratio and serum TSH levels between the two groups(P<0.05);the proportion of people in observation group who slept for less than 6 hours per day,frequently looked at their mobile phones,ate fried food≥1 time per week,and ate meat≥1 kg per week was higher than that in control group;however,the proportion of people in observation group who drank tea≥1 time per week,smoked≥1 time per week,had a salty daily taste,ate nuts≥1 time per week,and ate vegetables≥1 kg per week was lower than that in control group,and the differences were statistically significant(P<0.05).The results of multivariate logistic regression analysis showed that female,slept duration<6 hours/day,weekly meat consumption≥1 kg,and elevated serum TSH levels were risk factors for the onset of HT[odds ratios(OR)=3.37,4.11,2.48,1.14,and 95%confidence intervals(CI):1.08-10.55,1.46-11.59,1.00-6.51,1.00-1.30];eating≥1 kg of vegetables per week was a protective factor for the onset of HT(OR=0.36,95%CI:0.17-0.79).Conc

关 键 词：桥本甲状腺炎 生活方式 饮食习惯 危险因素 

分 类 号：R581.4[医药卫生—内分泌]