穴位贴敷对慢性失眠患者睡眠结构的影响  

Effect of acupoint application on sleep structure in patients with chronic insomnia

作　　者：赵娜[1] 谢晨[1,2] 付聪[1] 刘臻[1] 于心同[1] 杨文佳[1] 陈云飞[1] ZHAO Na;XIE Chen;FU Cong;LIU Zhen;YU Xintong;YANG Wenjia;CHEN Yunfei(Shanghai University of Traditional Chinese Medicine Yueyang Hospital of Traditional and Western Medicine,Shanghai 200437,China;Shanghai Research Institute of Acupuncture and Meridian,Shanghai 200030,China)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院,上海200437 [2]上海市针灸经络研究所,上海200030

出　　处：《上海针灸杂志》2023年第9期917-922,共6页Shanghai Journal of Acupuncture and Moxibustion

基　　金：上海市卫生和健康委员会科研项目(2022QN067,201540375);上海市自然科学基金项目(21ZR1464300);上海市针灸临床医学研究中心(20MC1920500)。

摘　　要：目的观察穴位贴敷对慢性失眠患者睡眠结构的影响。方法将68例慢性失眠患者随机分为治疗组和对照组,每组34例。治疗组给予安眠贴治疗,对照组给予安慰贴治疗。观察两组治疗前后多导睡眠图(polysomnography,PSG)相关睡眠参数和服药人数及服药量的变化。结果治疗组治疗后总睡眠时间(total sleep time,TST)、睡眠效率(sleep efficiency,SE)、睡眠后觉醒时间(wake after sleep onset,WASO)、睡眠潜伏期(sleep onset latency,SOL)、微觉醒指数优于治疗前(P<0.01),对照组治疗后SE、微觉醒总指数优于治疗前(P<0.01);治疗组治疗后SE、微觉醒总指数与对照组比较,差异有统计学意义(P<0.01)。治疗组治疗后非快动眼(non-rapid eye movement,NREM)睡眠N1期睡眠、N2期睡眠百分比与治疗前比较,差异有统计学意义(P<0.05);治疗组治疗后N1期睡眠、N2期睡眠百分比与对照组比较,差异有统计学意义(P<0.05)。治疗组治疗后服药人数百分比较治疗前降低(P<0.01);两组治疗后服药人数百分比比较,差异无统计学意义(P>0.05)。治疗组治疗后服药量较治疗前和对照组降低,差异有统计学意义(P<0.01)。结论穴位贴敷治疗慢性失眠能够明显提高睡眠效率,降低患者微觉醒指数,减少N1期睡眠百分比,增加N2期睡眠百分比,改善睡眠结构。Objective To observe the effect of acupoint application on sleep structure in patients with chronic insomnia.Method Sixty-eight patients with chronic insomnia were randomized to treatment and control groups,with 60 cases in each group.The treatment group was given sleep-inducing patches and the control group,placebo patches.Sleep-related parameters in polysomnography(PSG),the number of patients taking medication and the dosage taken were observed in the two groups before and after treatment.Result After treatment,the total sleep time(TST),sleep efficiency(SE),wake after sleep onset(WASO),sleep onset latency(SOL)and the microarousal index improved in the treatment group and SE and the total microarousal indexx improved in the control group compared with before(P<0.01).There were statistical significant post-treatment differences in SE and the total microarousal index between the treatment and control groups(P<0.01).The percentage of N1 and N2 sleep stages in non-rapid eye movement(NREM)sleep had statistical significant differences in the treatment group after treatment compared with before(P<0.05).There were statistical significant post-treatment differences in the percentage of N1 and N2 sleep stages between the treatment and control groups(P<0.05).The percentage of patients taking medication decreased in the treatment group after treatment compared with before(P<0.01).There were no statistical significant post-treatment difference in the percentage of patients taking medication between the two groups(P>0.05).After treatment,the dosage taken decreased in the treatment group compared with before and with the control group with a statistical significant difference(P<0.01).Conclusion Acupoint application can markedly enhance sleep efficiency,decrease the microarousal index,reduce the percentage of N1 stage sleep,increase the percentage of N2 stage sleep and improve sleep structure in treating patients with chronic insomnia.

关 键 词：穴位贴敷法 睡眠启动和维持困难 失眠 多导睡眠图 睡眠结构 

分 类 号：R246.1[医药卫生—针灸推拿学]