电针对甲基苯丙胺成瘾者脱毒早期戒断症状及焦虑抑郁情绪的影响  

Effect of electroacupuncture on withdrawal symptoms and anxiety and depression in patients with methamphetamine addiction during early detoxification

作　　者：顾尤 曾亮 潘国良 胡嘉威 梁艳[2] 俞捷 孔璟怡 曹世杰 GU You;ZENG Liang;PAN Guoliang;HU Jiawei;LIANG Yan;YU Jie;KONG Jingyi;CAO Shijie(Shanghai Pudong Hospital,Shanghai 201399,China;Shanghai University of Traditional Chinese Medicine Yueyang Hospital of Traditional Chinese and Western Medicine,Shanghai 200437,China;Shanghai Eighth People’s Hospital,Shanghai 200235,China;Tongji University Shanghai Fourth People’s Hospital,Shanghai 200081,China)

机构地区：[1]上海市浦东医院,上海201399 [2]上海中医药大学附属岳阳中西医结合医院,上海200437 [3]上海市第八人民医院,上海200235 [4]同济大学附属上海市第四人民医院,上海200081

出　　处：《上海针灸杂志》2023年第9期923-928,共6页Shanghai Journal of Acupuncture and Moxibustion

基　　金：国家自然科学基金青年项目(81403473);上海市青年科技英才扬帆计划(20YF1443200);上海市浦东新区卫生健康委员会临床中医特色学科建设项目(PDZY-2018-0611)。

摘　　要：目的观察电针对甲基苯丙胺成瘾者脱毒早期戒断症状及焦虑抑郁情绪的影响。方法将78例甲基苯丙胺成瘾者随机分成常规脱毒组(39例)和电针组(39例)。常规脱毒组以自然脱毒为主,电针组在自然脱毒基础上予电针治疗。观察两组在治疗前(T0)、治疗3 d后(T1)、治疗5 d后(T2)及治疗10 d(T3)后,视觉模拟量表(visual analog scale,VAS)、甲基苯丙胺戒断症状评分表、汉密尔顿焦虑量表(Hamilton anxiety scale,HAMA)及汉密尔顿抑郁量表(Hamilton depression scale,HAMD)评分变化。结果两组T1 VAS评分、甲基苯丙胺戒断症状评分、HAMA总分和HAMD总分均较T0升高(P<0.05);两组T2 VAS评分、甲基苯丙胺戒断症状评分、HAMA总分和HAMD总分较T0和T1显著降低(P<0.05);两组T3 VAS评分、甲基苯丙胺戒断症状评分、HAMA总分和HAMD总分较T0、T1和T2显著降低(P<0.05)。电针组T3 VAS评分低于常规脱毒组(P<0.05);T2和T3甲基苯丙胺戒断症状评分、HAMA总分和HAMD总分低于常规脱毒组(P<0.05)。结论电针可有效改善甲基苯丙胺成瘾者脱毒早期的心理渴求度、甲基苯丙胺戒断症状、焦虑和抑郁情绪,且治疗效果随着治疗时间增加。Objective To observe the effect of electroacupuncture on withdrawal symptoms and anxiety and depression in patients with methamphetamine addiction during early detoxification.Methods Seventy-eight patients with methamphetamine addiction were randomized to a conventional detoxification group(39 cases)and an electroacupuncture group(39 cases).The conventional detoxification group mainly received natural detoxification and the electroacupuncture group,electroacupuncture treatment in addition.The visual analog scale(VAS),the methamphetamine withdrawal symptom rating scale,the Hamilton anxiety rating scale(HAMA)and the Hamilton depression rating scale(HAMD)scores were recorded in the two groups before treatment(T0)and at three days(T1),five days(T2)and ten days(T3)after.Result The VAS score,the Methamphetamine Withdrawal Symptom Rating Scale score,the HAMA total score and the HAMD total score increased in the two groups at T1 compared with T0(P<0.05).The VAS score,the Methamphetamine Withdrawal Symptom Rating Scale score,the HAMA total score and the HAMD total score decreased significantly in the two groups at T2 compared with T0 and T1(P<0.05)and at T3 compared with T0,T1 and T2(P<0.05).At T3,the VAS score was lower in the electroacupuncture group than in the conventional detoxification group(P<0.05).At T2 and T3,the Methamphetamine Withdrawal Symptom Rating Scale score,the HAMA total score and the HAMD total score were lower in the electroacupuncture group than in the conventional detoxification group(P<0.05).Conclusion Electroacupuncture can effectively reduce the psychological craving and relieve methamphetamine withdrawal symptoms and anxiety and depression in patients with methamphetamine addiction during early detoxification.The therapeutic effect improves with the therapeutic time.

关 键 词：电针 甲基苯丙胺 物质戒断综合征 焦虑 抑郁 

分 类 号：R246.1[医药卫生—针灸推拿学]