Correlation between Polyphenol Contents and Antioxidant Activities in Different Echinacea Purpurea Varieties  

作　　者：Xiao-jing LIN Zheng-shi-yu LAI Qun LUO Mei KONG Min-jian LIANG Hong WU Mei BAI 

机构地区：[1]Guangdong Technology Research Center for Traditional Chinese Veterinary Medicine and Natural Medicine,South China Agricultural University,Guangzhou 510642,China [2]Qilu Animal Health Products Company,Jinan 250033,China [3]State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources,College of Life Sciences,South China Agricultural University,Guangzhou 510642,China

出　　处：《Current Medical Science》2023年第4期831-837,共7页当代医学科学（英文）

基　　金：supported by the Technology and Development Project of the Finance Department of Guangdong Province,China(No.[2015]639);the Technology Project of the Educational Commission of Guangdong Province of China(No.[2015]3)。

摘　　要：Objective:Polyphenols are complex compounds containing multiple phenolic hydroxyl groups.They are widely distributed in plants and have antioxidant activities.Whether the antioxidant activities of the cultivated varieties of Echinacea are similar to or better than those of the wild ones and the relationship between the accumulation of polyphenols and their antioxidant activities are still not clear.Methods:Folin-Ciocalteu method,high performance liquid chromatography(HPLC),2,2-diphenyl-1-picrylhydrazyl(DPPH)radical scavenging assay,ferric ion reducing antioxidant power(FRAP)assay,2,2'-azino-bis(3-ethylbenzothiazoline-6)-sulfonic acid(ABTS)radical scavenging assay,and Fe^(2+)chelating ability assay were used,respectively,to detect the total polyphenols and 5 kinds of caffeic acid derivatives(chicoric acid,caffeic acid,caftaric acid,chlorogenic acid,and 1,5-dicaffeoylquinic acid)in the roots,stems,leaves,and flowers,and the antioxidant activities of 3 varieties of Echinacea:E.purpurea L.,cultivar E.purpurea'Aloha',and E.purpurea'White Swan'.Results:E.purpurea L.had the highest contents of total polyphenols,5 caffeic acid derivatives and antioxidant activities,followed by E.purpurea'White Swan'and E.purpurea'Aloha',respectively.E.purpurea'White Swan'had the strongest ability to remove the DPPH,ABTS·^(+)and free radicals,and to chelate Fe^(2+);E.purpurea L.had the strongest ability to reduce FRAP.The correlation analyses revealed that the contents of total polyphenols and caffeic acid derivatives of E.purpurea L.and E.purpurea'White Swan'were correlated with their antioxidant activities.Conclusion:E.purpurea L.was the most appropriate material for the development of medicinal plants.E.purpurea'White Swan'could be used as a substitute for E.purpurea L.in terms of its antioxidant activity.

关 键 词：antioxidant activity caffeic acid derivatives Echinacea purpurea medicinal plants total polyphenol 

分 类 号：R282[医药卫生—中药学]