A new form of familial platelet disorder caused by germline mutations in RUNX1 in a pedigree  

作　　者：关军 GUAN Jun(Dept Hematol,Wuhan No.1 Hosp,Wuhan 430022)

机构地区：[1]Dept Hematol,Wuhan No.1 Hosp,Wuhan 430022

出　　处：《China Medical Abstracts(Internal Medicine)》2023年第2期123-124,共2页中国医学文摘（内科学分册（英文版）

摘　　要：Objective To investigate the clinical and biological characteristics of familial platelet disorder(FPD)with germline Runt-related transcription factor(RUNX)1 mutations.Methods Patients diagnosed with myelodysplastic syndrome(MDS)or acute myeloid leukemia(AML)with RUNX1 mutations from February 2016 to December 2021 in Wuhan No.1 Hospital underwent pedigree analysis and were screened for gene mutations(somatic and germline).

关 键 词：RUNX1 FAMILIAL ACUTE 

分 类 号：R558.2[医药卫生—血液循环系统疾病]