非O1/O139群霍乱弧菌致肝硬化患者血流感染  

Bloodstream infection caused by non-O1/O139 Vibrio cholerae in a patient with liver cirrhosis

作　　者：王志军 王向南 冯银霞 WANG Zhijun;WANG Xiangnan;FENG Yinxia(Department of Laboratory Medicine,Xing'an League People's Hospital,Xing'an League,Inner Mongolia 137400,China)

机构地区：[1]内蒙古自治区兴安盟人民医院检验科,内蒙古兴安盟137400

出　　处：《中国国境卫生检疫杂志》2023年第4期364-366,共3页Chinese Journal of Frontier Health and Quarantine

摘　　要：目的 探讨肝硬化患者血液培养中分离培养的霍乱弧菌的鉴定和分型。方法 通过革兰染色和VITEK2 Compact全自动细菌鉴定分析系统,鉴定1名肝硬化患者血标本中霍乱弧菌,用血清凝集试验鉴定血清型,纸片琼脂扩散法(K-B法)测定药物敏感性。结果 检出的霍乱弧菌为非O1/O139群霍乱弧菌,不引起霍乱。菌株对哌拉西林/他唑巴坦、头孢他啶、头孢哌酮/舒巴坦、头孢吡肟、美罗培南、左氧氟沙星、四环素、复方新诺明等药物敏感。结论 非O1/O139群霍乱弧菌引起的血流感染可发生于有肝病或免疫力低下的患者。Objective To investigate the identification and typing of Vibrio cholerae isolated from blood culture of a patient with liver cirrhosis.Methods The Vibrio cholerae strain was identified by Gram staining,VITEK2 Compact automatic bacterial identification and analysis system,the serotype was identified by serum agglutination test.The drug sensitivity was detected with K-B method.Results The Vibrio cholerae strain was non-O1/O139 group Vibrio cholerae,which did not cause cholera.The strain was sensitive to piperacillin/tazobactam,ceftazidime,cefoperazone/sulbactam,cefepime,meropenem,levofloxacin,tetracycline and cotrimoxazole.Conclusion Septicemia caused by non-O1/O139 group Vibrio cholerae might be occurred in patients with liver disease or low immunity.

关 键 词：非O1/O139群霍乱弧菌 肝硬化 血培养 

分 类 号：R254.7[医药卫生—中医内科学]