MDT模式在非酒精性脂肪性肝病干预中的应用价值  

Application value of MDT model in intervention of non-alcoholic fatty liver disease

作　　者：库尔班妮萨·吾拉音 苏桂华[1] Kurbanisa Urayin;SU Gui-hua(Department of Infection,the First People's Hospital of Kashgar,844200 Kashgar,Xinjiang,China)

机构地区：[1]喀什地区第一人民医院感染科,新疆喀什844200

出　　处：《临床消化病杂志》2023年第4期263-267,共5页Chinese Journal of Clinical Gastroenterology

摘　　要：[目的]分析多学科团队协作(MDT)模式在非酒精性脂肪性肝病(NAFLD)干预中的应用价值。[方法]选取确诊并住院治疗的156例NAFLD患者为研究对象,并按照随机数字法随机分为研究组和对照组(各78例)。其中对照组实施常规诊疗模式,研究组实施MDT模式。比较2组患者干预前后身体形态相关指标、血脂水平、肝肾功能、空腹血糖、胰岛功能状况。[结果]干预后,2组体质量、BMI、腰围、臀围、脂肪含量以及体脂肪率均明显降低,且研究组体质量、BMI、腰围、臀围、脂肪含量以及体脂肪率低于对照组(P<0.05);干预后,2组总胆固醇、三酰甘油、低密度脂蛋白胆固醇水平均明显降低,高密度脂蛋白胆固醇水平明显升高(P<0.05),且研究组上述指标优于对照组(P<0.05);干预后,2组谷丙转氨酶、谷草转氨酶、血清肌酐、空腹血糖、糖化血红蛋白、胰岛素抵抗水平均明显降低,胰岛β细胞功能指数水平明显升高(P<0.05),且研究组上述指标优于对照组(P<0.05)。[结论]MDT模式能够有效改善NAFLD患者身体形态,改善血脂、血糖及肝肾功能,提高临床干预效果,具有较好的临床应用价值。[Objective]To investigate the application value of Multi-disciplinary Team(MDT)model in intervention of non-alcoholic fatty liver disease(NAFLD).[Methods]A total of 156 NAFLD patients who were diagnosed and hospitalized in the First People's Hospital of Kashgar from May 2019 to May 2020 were selected as the research objects,and were randomly divided into a study group and a control group(78 cases in each group)according to the random number method.The control group implemented the routine diagnosis and treatment model,and the study group implemented the MDT model.The status of body shape-related indicators,blood lipid levels,liver and kidney function,fasting blood glucose,and pancreatic islet functionbefore and after intervention were compared in the two groups.[Results]After intervention,the body weight,BMI,waist circumference,hip circumference,fat content and body fat rate of the two groups were significantly reduced,and the weight,BMI,waist circumference,hip circumference,fat content and body fat rate of the study group were lower compared with the control group(P<0.05).After intervention,the levels of TC,TG,LDL-C in the two groups were significantly reduced(P<0.05),and the level of HDL-C was significantly increased(P<0.05),and the indicators in the study group were improved compared with the control group(P<0.05).After intervention,Scr,ALT,AST,fasting blood glucose,HbAlc,HOMA-IR levels were significantly reduced in the two groups,and HOMA-β levels were significantly increased(P<0.05),and the indicators of the study group were improved compared with the control group(P<0.05).[Conclusion]The multidisciplinary teamwork model can effectively improve the body shape of patients with non-alcoholic fatty liver disease,regulate the secretion of adipocytokines,and at the same time improve liver and kidney function,fasting blood sugar and insulin resistance,and improve the effect of clinical intervention.It has good clinical application value.

关 键 词：非酒精性脂肪性肝病 多学科团队协作模式 应用价值 

分 类 号：R575[医药卫生—消化系统]