甲状腺静态显像UR值在甲状腺毒症原因鉴别中的临床价值  

UR value of thyroid scintigraphy in differential diagnosis of thyrotoxicosis

作　　者：宋宏涛 罗诗雨 陈晓雅 王磊 Song Hongtao;Luo Shiyu;Chen Xiaoya;Wang Lei(Department of Nuclear Medicine,Shijingshan Teaching Hospital of Capital Medical University,Beijing 100043,China,China;Department of Nuclear Medicine,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China;Department of Endocrinology,Shijingshan Teaching Hospital of Capital Medical University,Beijing 100043,China)

机构地区：[1]首都医科大学石景山教学医院,北京市石景山医院核医学科,北京100043 [2]首都医科大学附属北京同仁医院核医学科,北京100730 [3]首都医科大学石景山教学医院,北京市石景山医院内分泌科,北京100043

出　　处：《中华全科医师杂志》2023年第9期960-963,共4页Chinese Journal of General Practitioners

摘　　要：回顾性分析2016年1月至2022年3月于北京市石景山医院就诊的Graves甲状腺功能亢进(甲亢)患者99例、甲状腺炎毒症期患者78例、其他患者28例(包括甲状腺功能正常的体检患者、甲状腺炎非毒症期患者及单纯甲状腺肿患者)的甲状腺静态显像相关数据,计算甲状腺单位像素计数(CT)与本底单位像素计数(CB)比值(UR);通过受试者工作特征(ROC)曲线确定其诊断Graves甲亢的最佳临界值。Graves甲亢组的UR值明显高于甲状腺炎毒症期组及其他组,三者关系为Graves甲亢组>其他组>甲状腺炎毒症期组,差异均有统计学意义(H=163.62,P<0.05)。ROC曲线分析结果,UR>4.84有助于Graves甲亢的诊断,其灵敏度为95.0%,特异度为98.1%。结果提示UR比值在Graves甲亢与非甲亢患者的鉴别中具有一定的参考价值。The clinical and imaging data of 99 patients with Graves′disease,78 patients with thyroiditis and 28 patients with other diseases(resolving thyroiditis,non thyroid disease and simple goiter)who underwent thyroid scintigraphy in Beijing Shijingshan Hospital from January 2016 to March 2022 were retrospectively reviewed.The UR value of thyroid scintigraphy was calculated and ROC curve was used to assess the UR value in diagnosis of Graves′disease.The UR value of patients with Graves′hyperthyroidism was significantly higher than that of patients with thyroiditis and other diseases(H=163.62,P<0.05).UR>4.84 was taken as optimal cutoff value to diagnose Graves′hyperthyroidism,with the sensitivity and specificity of 95.0%and 98.1%,respectively.

关 键 词：甲状腺毒症 GRAVES甲亢 甲状腺炎 甲状腺静态显像 促甲状腺素受体抗体 

分 类 号：R581.1[医药卫生—内分泌]