经皮PFO封堵术及其并发症的研究进展  

Research progress on percutaneous patent foramen ovale closure and its complications

作　　者：金力波 鲁勇 郭航远[2] Jin Libo;Lu Yong;Guo Hangyuan(Department of Cardiac Surgery,Shaoxing People's Hospital,Shaoxing Hospial of Zhejang Universiy,Shaoxing 312000,China;Department of Cardiology,Shaoxing People's Hospital,Shaoxing Hospital of Zhejiang University,Shaoxing 312000,China)

机构地区：[1]绍兴市人民医院,浙江大学绍兴医院心血管外科,绍兴312000 [2]绍兴市人民医院,浙江大学绍兴医院心血管内科,绍兴312000

出　　处：《中华胸心血管外科杂志》2023年第8期504-508,共5页Chinese Journal of Thoracic and Cardiovascular Surgery

基　　金：国家自然科学基金(82174204)。

摘　　要：卵圆孔未闭(patent foramen ovale,PFO)是一种先天性的允许心房右向左分流的结构性病变,已被越来越多的人认为是隐源性卒中的主要病因,其机制归因于通过PFO分流进入动脉循环的反常栓塞。大量国内外研究已证实了经皮PFO封堵术在隐源性卒中、偏头痛等疾病二级预防的有效性和安全性。其总体来说是一项成熟、安全的术式,但相应的并发症仍不可避免。本文在阐述PFO封堵术式的基础上进一步介绍了其相关并发症,旨在加强临床医师对经皮PFO封堵术及其并发症的认识,以减少临床工作中一些不必要的问题。Patent foramen ovale(PFO),a congenital structural lesion that allows shunting of blood from the right to the left atrium,has been increasingly recognized as the main cause of cryptogenic stroke.The mechanism of PFO-related cryptogenic stroke is attributed to paradoxical embolism into the arterial system via PFO.A large number of domestic and foreign studies have confirmed the efficacy and safety of percutaneous PFO closure in the secondary prevention of a series of diseases including cryptogenic stroke and migraine.Percutaneous PFO closure is a mature and safe operation overall,but its corresponding complications are still unavoidable.We mainly introduce PFO closure and its related complications in this paper,aiming to enhance clinicians'understanding of this operation and its complications,so as to reduce some unnecessary troubles in clinical work.

关 键 词：右向左分流 封堵术 卵圆孔未闭 隐源性卒中 二级预防 PFO 临床医师 反常栓塞 

分 类 号：R54[医药卫生—心血管疾病]