麦角硫因的药理作用研究进展  

Progress on pharmacological effects of ergothioneine

作　　者：葛珈铭 弓思涵 韩翠婷 王广苹 赵盈 李先宽[1] 於洪建 GE Jia-ming;GONG Si-han;HAN Cui-ting;WANG Guang-ping;ZHAO Ying;LI Xian-kuan;YU Hong-jian(Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;Hefei Hechen Biotechnology Co.,Ltd.,Hefei 230061,China;Tianjin University of Science and Technology,Tianjin 300457,China)

机构地区：[1]天津中医药大学,天津301617 [2]合肥和晨生物科技有限公司,安徽合肥230061 [3]天津科技大学,天津300457

出　　处：《现代药物与临床》2023年第8期2093-2099,共7页Drugs & Clinic

基　　金：天津市道地药材生态种植及质量保障项目(2022)。

摘　　要：麦角硫因是一种天然的硫咪唑氨基酸类强抗氧化剂,主要存在于灵芝等食用菌、药用菌中。麦角硫因具有良好的抗氧化、抗炎作用,可作用于糖尿病、心血管疾病、神经系统疾病、肠道疾病、肝脏疾病、子痫前期和肺损伤。综述了麦角硫因的药理作用,以期为麦角硫因的开发应用提供参考依据。Ergothioneine is a natural strong antioxidant of thiimidazole amino acids,which mainly exists in edible and medicinal fungi,such as Ganoderma lucidum.Ergothioneine has good antioxidant and anti-inflammatory effects,and can act on diabetes,cardiovascular diseases,nervous system diseases,intestinal disease,liver disease,pre-eclampsia,and lung injury.This article reviews the pharmacological effects of ergothioneine in order to provide a reference for development and use of ergothioneine.

关 键 词：麦角硫因 抗氧化 抗炎 糖尿病 肝脏疾病 子痫前期 肺损伤 

分 类 号：R285[医药卫生—中药学]