Risk factors of concurrent urinary sepsis in patients with diabetes mellitus comorbid with upper urinary tract calculi  

作　　者：Jian-Jie Gou Chao Zhang Hai-Song Han Hong-Wei Wu 

机构地区：[1]Department of Urology Surgery,People’s Hospital of Jincheng,Jincheng 048000,Shanxi Province,China [2]Emergency Department,People’s Hospital of Jincheng,Jincheng 048000,Shanxi Province,China

出　　处：《World Journal of Diabetes》2023年第9期1403-1411,共9页世界糖尿病杂志（英文版）（电子版）

摘　　要：BACKGROUND Urinary sepsis is frequently seen in patients with diabetes mellitus(DM)complicated with upper urinary tract calculi(UUTCs).Currently,the known risk factors of urinary sepsis are not uniform.AIM To analyze the risk factors of concurrent urinary sepsis in patients with DM complicated with UUTCs by logistic regression.METHODS We retrospectively analyzed 384 patients with DM complicated with UUTCs treated in People’s Hospital of Jincheng between February 2018 and May 2022.The patients were screened according to the inclusion and exclusion criteria,and 204 patients were enrolled.The patients were assigned to an occurrence group(n=78)and a nonoccurrence group(n=126).Logistic regression was adopted to analyze the risk factors for urinary sepsis,and a risk prediction model was established.RESULTS Gender,age,history of lumbago and abdominal pain,operation time,urine leukocytes(U-LEU)and urine glucose(U-GLU)were independent risk factors for patients with concurrent urinary sepsis(P<0.05).Risk score=0.794×gender+0.941×age+0.901×history of lumbago and abdominal pain-1.071×operation time+1.972×U-LEU+1.541×U-GLU.The occurrence group had notably higher risk scores than the nonoccurrence group(P<0.0001).The area under the curve of risk score for forecasting concurrent urinary sepsis in patients was 0.801,with specificity of 73.07%,sensitivity of 79.36%and Youden index of 52.44%.CONCLUSION Sex,age,history of lumbar and abdominal pain,operation time,ULEU and UGLU are independent risk factors for urogenic sepsis in diabetic patients with UUTC.

关 键 词：Diabetes mellitus Upper urinary tract calculi Urinary sepsis Risk factors Risk prediction model Logistic regression Concurrent urinary sepsis 

分 类 号：R587.2[医药卫生—内分泌] R692.9[医药卫生—内科学]