Synthesis of Tribolure,the Common Aggregation Pheromone of Four Tribolium Flour Beetles  

作　　者：Chao Wang Chengyu He Yong Shi Hua Xiang Weisheng Tian 

机构地区：[1]Department of Medicinal Chemistry,School of Pharmacy,Chinese Pharmaceutical University,Nanjing,Jiangsu 210009,China [2]CAS Key Laboratory of Synthetic Chemistry of Natural Substances,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,China

出　　处：《Chinese Journal of Chemistry》2015年第6期627-631,共5页中国化学（英文版）

摘　　要：Herein we report a synthesis of the natural tribolure,an aggregation pheromone which consists of(4R,8S)-,(4R,8R)-,(4S,8S)-,and(4S,8R)-4,8-dimethyldecanals in a ratio of 4/4/1/1,from(R)-4-methyl-δ-valerolactone,a by-product of the degradation of steroidal sapogenins.Merging the stereoisomers of the same ratios into one synthetic target and using the same chiron for the construction of the C4 stereocenters are notable features of this synthesis.

关 键 词：aggregation pheromone tribolure SYNTHESIS Tribolium flour beetle (R)-4-methyl-δ-valerolactone 

分 类 号：O62[理学—有机化学]