DBU-Mediated Carboxylative Coupling of Primary Amines,Carbon Dioxide and Propargyl Chlorides  

作　　者：Wen-Zhen Zhang Xiang Ren Xiao-Bing Lu 

机构地区：[1]State Key Laboratory of Fine Chemicals,Dalian University of Technology,Dalian,Liaoning 116024,China

出　　处：《Chinese Journal of Chemistry》2015年第5期610-613,共4页中国化学（英文版）

基　　金：National Natural Science Foundation of China(No.21172026);Scientific Research Fund of Liaoning Provincial Education Department(No.L2012024);X.-B.L.gratefully acknowledges the Chang Jiang Scholars Program(No.T2011056)from Ministry of Education of the People's Republic of China.

摘　　要：A carboxylative coupling reaction of various primary amine and 3-phenyl-2-propynyl or 2-nonynyl chloride in the presence of 8-diazabicyclo[5.4.0]undec-7-ene(DBU)using carbon dioxide as carboxylative reagent was presented.This transition-metal free reaction system shows broad substrate scope and gives a series of propargylcarbamates in moderate to good yield.The obtained N-alkyl substituted carbamate product can undergo base-catalyzed intramolecular cyclization reaction to afford functionalized 4-methylene-2-oxazolidinone in good yield.

关 键 词：carbon dioxide fixation AMINES propargylchlorides carboxylative coupling transition-metal free 

分 类 号：O62[理学—有机化学]