妊娠期糖尿病患者血清中人软骨糖蛋白39、弹性蛋白酶抑制剂、血清促代谢因子的表达及其与胰岛素抵抗的关系  

Expression of YKL-40,SerpinB1 and Betatrophin in serum of patients with gestational diabetes mellitus and their relationship with insulin resistance

作　　者：张秋妍 郭慧涛 毕慧霞 朱改变 Zhang Qiuyan;Guo Huitao;Bi Huixia;Zhu Gaibian(Maternity and Maternity Health Comprehensive Clinic,Children’s Hospital of Shanxi,Women Health Center of Shanxi,Taiyuan 030006,China;Department of Obstetrics,Children’s Hospital of Shanxi,Women Health Center of Shanxi,Taiyuan 030006,China)

机构地区：[1]山西省儿童医院、山西省妇幼保健院妇产保健综合门诊,太原030006 [2]山西省儿童医院、山西省妇幼保健院产科,太原030006

出　　处：《中华生物医学工程杂志》2023年第3期302-305,共4页Chinese Journal of Biomedical Engineering

摘　　要：研究妊娠期糖尿病(GDM)患者血清中人软骨糖蛋白39(YKL-40)、弹性蛋白酶抑制剂(SerpinB1)、血清促代谢因子(Betatrophin)的表达及其与胰岛素抵抗的关系。研究发现GDM患者血清中YKL-40、SerpinB1、betatrophin的表达与胰岛素抵抗呈现出显著的相关性,可为临床诊断提供科学依据。To investigate the expression of human cartilage glycoprotein 39(YKL-40),elastase inhibitor(SerpinB1)and serum pro-metabolic factor(Betatrophin)in the serum of patients with gestational diabetes mellitus(GDM)and their relationship with insulin resistance.The expression of YKL-40,SerpinB1 and betatrophin in the serum of GDM patients showed a significant correlation with insulin resistance,which could provide a scientific basis for clinical diagnosis.

关 键 词：妊娠期糖尿病 人软骨糖蛋白39 弹性蛋白酶抑制剂 血清促代谢因子 胰岛素抵抗 

分 类 号：R714.256[医药卫生—妇产科学]