Predictive value of preoperative albumin-bilirubin score and other risk factors for short-term outcomes after open pancreatoduodenectomy  

作　　者：Hana Zavrtanik Davide Cosola David Badovinac Benjamin Hadžialjević Gašper Horvat Danaja Plevel Selene Bogoni Paola Tarchi Nicolòde Manzini AlešTomažič 

机构地区：[1]Department of Abdominal Surgery,University Medical Centre Ljubljana,Ljubljana 1000,Slovenia [2]Clinica Chirurgica,Azienda Sanitaria Universitaria Giuliano Isontina,Cattinara Hospital,Trieste 34149,Italy [3]Department of Medical,Surgical and Health Sciences,University of Trieste,Trieste 34149,Italy [4]Faculty of Medicine,University of Ljubljana,Ljubljana 1000,Slovenia

出　　处：《World Journal of Clinical Cases》2023年第26期6051-6065,共15页世界临床病例杂志

摘　　要：BACKGROUND Pancreatoduodenectomy represents a complex procedure involving extensive organ resection and multiple alimentary reconstructions.It is still associated with high morbidity,even in high-volume centres.Prediction tools including preoperative patient-related factors to preoperatively identify patients at high risk for postoperative complications could enable tailored perioperative management and improve patient outcomes.AIM To evaluate the clinical significance of preoperative albumin-bilirubin score and other risk factors in relation to short-term postoperative outcomes in patients after open pancreatoduodenectomy.METHODS This retrospective study included all patients who underwent open pancreatic head resection(pylorus-preserving pancreatoduodenectomy or Whipple resection)for various pathologies during a five-year period(2017-2021)in a tertiary care setting at University Medical Centre Ljubljana,Slovenia and Cattinara Hospital,Trieste,Italy.Short-term postoperative outcomes,namely,postoperative complications,postoperative pancreatic fistula,reoperation,and mortality,were evaluated in association with albumin-bilirubin score and other risk factors.Multiple logistic regression models were built to identify risk factors associated with these short-term postoperative outcomes.RESULTS Data from 347 patients were collected.Postoperative complications,major postoperative complications,postoperative pancreatic fistula,reoperation,and mortality were observed in 52.7%,22.2%,23.9%,21.3%,and 5.2%of patients,respectively.There was no statistically significant association between the albumin-bilirubin score and any of these short-term postoperative complications based on univariate analysis.When controlling for other predictor variables in a logistic regression model,soft pancreatic texture was statistically significantly associated with postoperative complications[odds ratio(OR):2.09;95%confidence interval(95%CI):1.19-3.67];male gender(OR:2.12;95%CI:1.15-3.93),soft pancreatic texture(OR:3.06;95%CI:1.56-5.97),and blo

关 键 词：PANCREATODUODENECTOMY ALBUMIN BILIRUBIN Postoperative complications Pancreatic fistula Perioperative care 

分 类 号：R699.2[医药卫生—泌尿科学]