Variant of Guillain-Barrésyndrome with anti-sulfatide antibody positivity and spinal cord involvement:A case report  

作　　者：Hua Liu Hui-Gang Lv Rong Zhang 

机构地区：[1]Department of Neurology,Yixing Hospital of Traditional Chinese Medicine,Yixing 214200,Jiangsu Province,China [2]Department of Neurology,The First People's Hospital of Shizuishan City,Shizuishan 753200,Ningxia Hui Autonomous Region,China

出　　处：《World Journal of Clinical Cases》2023年第26期6274-6279,共6页世界临床病例杂志

基　　金：Yixing Administration of Traditional Chinese Medicine,No.yxfc03。

摘　　要：BACKGROUND Guillain-Barrésyndrome(GBS)is an acute autoimmune-mediated polyneuropathy.Studies have increasingly reported the presence of anti-sulfatide antibody positivity with varying clinical symptoms in patients with GBS.However,spinal cord involvement is relatively rare in these cases.CASE SUMMARY A 68-year-old woman was admitted to the hospital with weakness of the limb for more than 3 d.Additional symptoms included neck pain,progressive numbness in the distal extremities,urinary and fecal retention,and reduced perception of temperature.She was diagnosed with an anti-sulfatide antibody-positive GBS variant and discharged after treatment with methylprednisolone and intravenous human immunoglobulin pulse therapy.Unlike common cases of anti-sulfatide antibody-positive GBS,this patient had atypical clinical symptoms of spinal cord involvement.No similar cases have previously been reported in China.CONCLUSION Although GBS is associated with a poor prognosis,a prompt diagnosis allows early administration of combined intravenous human immunoglobulin and methylprednisolone pulse therapy.

关 键 词：Guillain-Barrésyndrome spinal cord involvement anti-sulfatide antibodypositive Case report 

分 类 号：R244.1[医药卫生—针灸推拿学]