体外冲击波治疗骨不愈合机制的研究进展  

Mechanism of extracorporeal shock wave therapy for nonunion of bone

作　　者：安国尧[1] 高明暄 张俐 南学彦[1] 郑恒恒[1] 李百通 靳博 AN Guoyao;GAO Mingxuan;ZHANG Li;NAN Xueyan;ZHENG Hengheng;LI Baitong;JIN Bo(Department of Joint Minimally Invasive Orthopedics,Gansu Provincial Hospital of Traditional Chinese Medicine,Gansu Province,Lanzhou 730050,China;Fujian College of Biotechnology,Fujian Province,Fuzhou 350118,China)

机构地区：[1]甘肃省中医院关节微创骨科,甘肃兰州730050 [2]福建生物工程职业技术学院,福建福州350118

出　　处：《中国当代医药》2023年第25期38-42,共5页China Modern Medicine

摘　　要：随着科技的发展,各种高能量损伤导致骨折的患者越来越多,高能量骨折患者中骨不愈合病例也随之增多,给临床治疗也带来了极大的困难。骨不愈合是骨科临床中的一大难题,在骨不愈合的治疗过程中,除了清理骨折断端死骨、再通髓腔、自体骨移植及更换固定方式外,物理治疗也在骨不愈合治疗过程中发挥极其重要的作用,体外冲击波就是其中一种,体外冲击波目前是一种无创、安全、有效的物理治疗方法,它能改善骨折断端局部微循环,诱导生长因子释放,促进细胞活性,增加细胞代谢,促进炎症反应,诱导细胞表达、调控信号通路达到促进骨折愈合的作用,在临床治疗骨不愈合中有广阔的前景。With the development of science and technology,there are more and more patients with high-energy injuries leading to fractures,and there are also more cases of bone nonunion among high-energy fracture patients,which also brings great difficulties to clinical treatment.Bone nonunion is a major problem in orthopaedic clinic.In the treatment of bone nonunion,physical therapy also plays an extremely important role in the treatment of bone nonunion,including cleaning the dead bone at the broken end of the fracture,reopening the medullary cavity,autogenous bone transplantation and replacing the fixation method.Extracorporeal shock wave is one of them.At present,extracorporeal shock wave is a non-invasive,safe and effective physical therapy method.It can improve the local microcirculation at the fracture end,induce the release of growth factors,promote cell activity,increase cell metabolism,promote inflammatory response,induce cell expression,regulate signal pathways to promote fracture healing,and has broad prospects in clinical treatment of bone nonunion.

关 键 词：体外冲击波 骨不愈合 物理治疗 机制 

分 类 号：R683[医药卫生—骨科学]