中药“盆炎方”治疗盆腔炎患者疗效观察  

Curative Effect of Penyan Decoction(盆炎方)on Patients with Chronic Pelvic Inflammatory Disease

作　　者：李思佳 顾晓枫 高悦 LI Sijia;GU Xiaofeng;GAO Yue(Suzhou Hospital of Integrated Traditional Chinese and Western Medicine,Suzhou 215000,Jiangsu,China)

机构地区：[1]苏州市中西医结合医院,江苏苏州215000

出　　处：《辽宁中医杂志》2023年第6期74-77,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：苏州市中西医结合医院院级课题(YJ2020010)。

摘　　要：目的探讨中药“盆炎方”治疗对湿热瘀结型盆腔炎(CPID)患者临床疗效观察。方法选取2020年1月—2021年6月在该结合医院收治的CPID患者90例,采用简单随机数表发分为3组,每组30例。对照1组予以“盆炎方”中药保留灌肠,对照2组予头孢唑肟钠注射液静脉治疗,观察组予以“盆炎方”中药保留灌肠联合抗生素静脉注射治疗,持续用药14 d。治疗后比较3组临床疗效、中医症状评分、实验室检查结果和彩超,出院3个月比较3组生活质量;出院半年比较3组复发率。结果治疗后观察组、对照1组和对照2组总有效率分别为93.33%(28/30)、80.00%(24/30)和83.33%(25/30),差异无统计学意义(P>0.05);治疗后3组疼痛、带下异常与月经异常中医证候评分均低于治疗前,且观察组低于对照1组和对照2组(P<0.05)。治疗后3组白细胞计数(WBC)、血沉(ESR)、超敏C反应蛋白(CRP)、搏动指数(PI)与阻力指数(RI)水平均低于治疗前,且观察组低于对照1组和对照2组(P<0.05),治疗后3组世界卫生组织生活质量测定量表(WHOQOL-100)评分均高于治疗前,且观察组高于对照1组和对照2组(P<0.05);对照2组和观察组复发率明显低于对照1组(χ^(2)=6.860,P<0.05)。结论中药“盆炎方”保留灌肠联合抗生素治疗应用于湿热瘀结型CPID患者可降低患者中医症状评分,改善炎症水平和血流动力学水平,并提高生活质量,降低术后复发率。Objective To explore the clinical curative effect of Penyan Decoction(盆炎方)on patients with chronic pelvic inflammatory disease(CPID)of damp-heat and blood stasis syndrome.Methods A total of 90 patients with CPID admitted to Suzhou Hospital of Integrated Traditional Chinese and Western Medicine were enrolled between January 2020 and June 2021.According to simple random number table method,they were divided into control 1 group(Penyan Decoction for retention enema),control 2 group(intravenous injection of ceftizoxime sodium)and observation group(Penyan Decoction for retention enema combined with intravenous injection of antibiotics),30 cases in each group.All were treated for 14 d.After treatment,the clinical curative effect,scores of TCM symptoms,examination results of laboratory test and color Doppler ultrasound were compared among the three groups.The quality of life 3 months after discharge and the recurrence rate half a year after discharge among the three groups were compared.Results After treatment,the difference in the total response rate among observation group,control 1 group and control 2 group was not statistically significant[93.33%(28/30),80.00%(24/30),83.33%(25/30)](P>0.05).After treatment,the scores of TCM symptoms(pain,abnormal vaginal discharge,menstrual abnormalities)in the three groups were decreased,which were lower in the observation group than those in the control 1 group and control 2 group(P<0.05).After treatment,the levels of white blood cell count(WBC),erythrocyte sedimentation rate(ESR),high-sensitivity C-reactive protein(CRP),pulsatility index(PI)and resistance index(RI)in the three groups were decreased,which were lower in the observation group than those in the control 1 group and control 2 group(P<0.05).After treatment,the scores of World Health Organization Quality of Life Scale(WHOQOL-100)in the three groups were increased,which were higher in the observation group than those in the control 1 group and control 2 group(P<0.05).The recurrence rate in the control 2 group and obs

关 键 词：盆炎方灌肠 慢性盆腔炎 生活质量 搏动指数 阻力指数 

分 类 号：R711.33[医药卫生—妇产科学]