中药熏蒸技术对肛肠疾病术后患者的疗效及安全性分析  

Efficacy and safety of traditional Chinese medicine fumigation in postoperative patients with anorectal disease

作　　者：钱晶晶 施捷 QIAN Jingjing;SHI Jie(Department of Traditional Chinese Medicine Surgery,Chongming Branch,Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 202150)

机构地区：[1]上海交通大学医学院附属新华医院崇明分院中医外科,上海202150

出　　处：《河北中医》2023年第8期1265-1268,共4页Hebei Journal of Traditional Chinese Medicine

基　　金：上海市进一步加快中医药事业发展三年行动计划[编号:ZY(2018-2020)-FWTX-7001]。

摘　　要：目的观察中药熏蒸技术对肛肠疾病术后患者的疗效及安全性。方法将100例肛肠疾病并进行手术的患者按照随机数字表法分为2组,对照组50例术后采用高锰酸钾坐浴,中药组50例术后采用中药熏蒸技术。2组均治疗14天。比较2组治疗前及治疗3、7、14天疼痛视觉模拟评分(VAS)、症状消失及创面愈合时间、血清P物质(SP)及干扰素γ(IFN-γ)水平,并统计2组疗效及不良反应发生情况。结果中药组总有效率96.00%(48/52),对照组总有效率82.00%(41/52),中药组临床疗效优于对照组(P<0.05)。2组治疗3、7、14天疼痛VAS均逐渐降低(P<0.05),且中药组治疗后疼痛VAS均低于对照组同期(P<0.05)。中药组肛门坠胀消失、创面水肿消失、创面渗液消失及创面愈合时间均短于对照组(P<0.05)。2组治疗后血清SP均较本组治疗前升高(P<0.05),IFN-γ均降低(P<0.05),中药组治疗后血清SP高于对照组(P<0.05),IFN-γ低于对照组(P<0.05)。中药组不良反应发生率4.00%(2/50),对照组不良反应发生率20.00%(10/50),中药组不良反应发生率低于对照组(P<0.05)。结论肛肠疾病术后运用中药熏蒸技术可以提高临床疗效,改善临床症状,减少患者术后不良反应,减轻患者术后疼痛,促进创面愈合。Objective To observe the efficacy and safety of traditional Chinese medicine(TCM)fumigation in postoperative patients with anorectal disease.Methods Totally 100 postoperative patients with anorectal disease were randomly assigned to TCM group(n=50)and the control group(n=50),in which they were treated with TCM fumigation and potassium permanganate bath,respectively.Treated for 14 days,the aim was to compare visual analogue scale(VAS),symptom disappearance time,wound healing time,substance P(SP),interferon-γ(IFN-γ)on day 0 and on days 3,7,14.The curative effect and adverse reactions were assessed.Results The overall effective rate in TCM group was better than that in control group(96.00%[48/52]vs 82.00%[41/52],P<0.05).After treatment,VAS scores on days 3,7,14 in groups were significantly decreased(P<0.05),which were more pronounced in TCM group compared with concurrent control group(P<0.05).The symptom(anal bulge,wound edema,wound effusion)disappearance time,wound healing time in TCM group were significantly shorter than those in control group(P<0.05).Significantly increased SP,and significantly decreased IFN-γwere detected in the two groups(both P<0.05),and the TCM group was superior to the control group for SP and IFN-γ(both P<0.05).The incidence of adverse reactions in TCM group was significantly lower than that in control group(4.00%[2/50]vs 20.00%[10/50],P<0.05).Conclusion For postoperative patients with anorectal disease,TCM fumigation can improve clinical efficacy and clinical symptoms,reduce postoperative adverse reactions,relieve postoperative pain and promote wound healing.

关 键 词：肛肠疾病 术后 熏蒸疗法 疗效 安全性 

分 类 号：R657.1[医药卫生—外科学]