生长抑素联合超声波药物透入治疗术后早期炎性肠梗阻的临床研究  

Clinical study of somatostatin combined with ultrasonic drug penetration in the treatment of early postoperative inflammatory intestinal obstruction

作　　者：李权 李由[1] 李洲[1] 冷蔚 LI Quan;LI You;LI Zhou;LENG Wei(Department of General Surgery,Zigong First People's Hospital,Zigong,Sichuan 643000,China)

机构地区：[1]自贡市第一人民医院普外科,四川自贡643000

出　　处：《现代医药卫生》2023年第17期2921-2924,共4页Journal of Modern Medicine & Health

基　　金：自贡市卫生健康委员会科研课题项目(19yb004)。

摘　　要：目的探讨生长抑素联合超声波药物透入治疗对术后早期炎性肠梗阻的影响及应用效果。方法将该院在2019年9月至2021年8月所收治的54例术后早期炎性肠梗阻患者作为研究对象,并将其分为A组、B组、C组,各18例。常规治疗下,对A组同时选用超声波导入新斯的明注射液10 mg,每天1次,每次30 min;B组患者采用生长抑素治疗;C组患者采用A组联合B组的治疗方式。观察3组患者的胃肠减压量、腹胀缓解时间、肛门排气排便恢复时间和手术中转率。结果在胃肠减压量方面,C组量最少,B组其次,A组量最大,C组与其他2组比较,差异均有统计学意义(P<0.05);在腹胀缓解时间方面,C组缓解时间最短,A组其次,最后是B组,C组与其他2组比较,差异均有统计学意义(P<0.05);在肛门排气排便时间方面,C组恢复的时间最快,A组其次,B组恢复的最慢,C组与其他2组,差异均有统计学意义(P<0.05),A组与B组比较,差异无统计学意义(P>0.05);在手术中转率方面,C组为0,A、B组均为22.22%,C组与其他2组比较,差异均有统计学意义(P<0.05)。结论生长抑素联合超声波药物透入治疗对术后早期炎性肠梗阻具有较高的应用价值,可以减少患者胃肠减压量、加速肛门排气排便、缓解患者腹胀症状、降低手术中转率,促进患者机体的恢复。Objective To investigate the effect of somatostatin combined with ultrasonic drug penetration therapy on early postoperative inflammatory intestinal obstruction.Methods A total of 54 patients with early postoperative inflammatory intestinal obstruction admitted to this hospital from September 2019 to August 2021 were selected as the research objects and were divided into group A,B and C,with 18 cases in each group.Under conventional treatment,group A was also given neostigmine injection 10 mg by ultrasound,once a day for 30 min each time;group B was treated with somatostatin.Patients in group C were treated with a combination of group A and group B.Gastrointestinal decompression volume,abdominal distension relief time,anal defecation recovery time and surgical conversion rate were observed in three groups.Results In the comparison of gastrointestinal decompression,group C had the least amount,followed by group B,and the volume of group A was the largest.The difference between group C and the other two groups was statistically significant(P<0.05).In the relief time to relieve abdominal distension,the relief time of group C was the shortest,followed by group A and group B,and the difference between group C and the other two groups was statistically significant(P<0.05).In the time of anal exhaust defecation,the recovery time of group C was the fastest,followed by group A,and group B was the slowest.The difference between group C and the other two groups was statistically significant(P<0.05),while the difference between group A and group B was not statistically significant(P>0.05).The rate of surgical conversion rate,in group C was zero,that in group B was 22.22%,and that in group A was 22.22%,and the differences between group C and the other two groups were statistically significant(P<0.05).Conclusion Somatostatin combined with ultrasound drug penetration therapy has high application value for early postoperative inflammatory intestinal obstruction,which can re-duce the amount of gastrointestinal decompression,accel

关 键 词：生长抑素 早期炎性肠梗阻 新斯的明 术后康复 

分 类 号：R453.9[医药卫生—治疗学] R459.4[医药卫生—临床医学]