抗菌可降解聚乳酸薄膜制备与性能测试  

Preparation and properties of antibacterial biodegradable poly(lactic acid)membrane

作　　者：关国涛 刘晨泽 何世权 宋超洋 张响[1,4,5] 赵娜 王超[3] GUAN Guotao;LIU Chenze;HE Shiquan;SONG Chaoyang;ZHANG Xiang;ZHAO Na;WANG Chao(School of Mechanics and Safety Engineering,Zhengzhou University,Zhengzhou 450001,China;School of Nursing and Health,Zhengzhou University,Zhengzhou 450001,China;No.406 Hospital of Zhengzhou,Zhengzhou 450001,China;National Center for International Joint Research of Micro‐Nano Molding Technology,Zhengzhou 450001,China;Key Laboratory for Micro Molding Technology of Henan Province,Zhengzhou 450001,China)

机构地区：[1]郑州大学力学与安全工程学院,郑州450001 [2]郑州大学护理与健康学院,郑州450001 [3]郑州四六零医院,郑州450001 [4]国家级微纳成型技术国际联合研究中心,郑州450001 [5]河南省微成型技术重点实验室,郑州450001

出　　处：《中国塑料》2023年第9期8-13,共6页China Plastics

摘　　要：将季铵盐与聚乳酸溶液共混并通过静电纺丝技术成功制备了抗菌可降解薄膜材料。利用扫描电子显微镜、电子万能材料试验机、纤维直径统计分布、抗菌性能测试等对纤维薄膜的结构和性能进行了表征。结果表明,单链季铵盐可在一定程度上提高聚乳酸薄膜材料的抗菌性能,但会降低薄膜的断裂强度和弹性模量。双链季铵盐能较大程度提高聚乳酸薄膜材料抗菌性能的同时保证薄膜材料具有良好的拉伸/断裂强度和延伸率,成膜均匀,抗菌剂分散性好,适于工业化生产和应用。In this study,an antibacterial degradable membrane was successfully prepared through electrostatic spinning using a mixture of quaternary ammonium salt and poly(lactic acid)(PLA),and their structure and properties were char‐acterized by using scanning electron microscope,electronic universal material testing machine,statistical distribution of fi‐ber diameter,and antibacterial property measurement.The results indicated that the single chain quaternary ammonium salt improve the antibacterial performance of the PLA membrane to a certain extent but reduced its breaking strength and elastic modulus.The double‐chain quaternary ammonium salt improved the antibacterial performance of the PLA mem‐brane significantly.This ensures that the membrane achieves high tensile/breaking strength and elongation,good mem‐brane formation uniformity,and good dispersity of antibacterial agents.Therefore,the PLA membrane filled with the double‐chain quaternary ammonium salt is more suitable for industrial production and practical applications.

关 键 词：季铵盐 聚乳酸 静电纺丝 抗菌薄膜 

分 类 号：TQ321[化学工程—合成树脂塑料工业]