唐古特红景天化学成分和药理作用的研究进展  

Research progress on chemical components and pharmacological effect of Rhodiola algida

作　　者：南星梅 于洋[1] 杨进[2] 芦殿香 NAN Xing-mei;YU Yang;YANG Jin;LU Dian-xiang(Medical College of Qinghai University,Xining 810001,China;Affiliated Hospital of Chengdu University,Chengdu 610081,China)

机构地区：[1]青海大学医学部,青海西宁810001 [2]成都大学附属医院,四川成都610081

出　　处：《中草药》2023年第16期5433-5441,共9页Chinese Traditional and Herbal Drugs

基　　金：国家自然科学基金资助项目(82060786);国家自然科学基金资助项目(32060088);青海省自然科学基金青年项目(2020-ZJ-950Q)。

摘　　要：唐古特红景天Rhodiola algida是青藏高原地区特有的药用植物,具有高原人参之美称,主要化学成分包括醇类、黄酮类、苯丙素类、有机酸类、烷烃类及萜类等,具有抗缺氧、抗氧化、抗癌、抑制脯氨酰寡肽酶活性、抗衰老、保护肝脑等药理作用。通过对近年来关于唐古特红景天化学成分、药理活性和毒理研究进行综述,以期提高人们对传统药用植物的认识、利用及保护意识,为唐古特红景天进一步的综合开发利用提供参考。Tanggute Hongjingtian(Rhodiola algida var.tangutica)is a unique medicinal plant in Qinghai-Tibet Plateau,which has the reputation of plateau ginseng.Its main chemical components include alcohols,flavonoids,phenylpropanoids,organic acids,alkanes and terpenoids.Its pharmacological effects have been studied,including anti-hypoxia,anti-oxidation,anti-cancer,inhibition of prolyl oligopeptide activity,anti-aging,liver and brain protection.In this paper,the research on chemical composition,pharmacological activity and toxicology of R.algida var.tangutica in recent years was reviewed,in order to improve people’s understanding,utilization and protection awareness of traditional Chinese medicine,and to provide reference for further comprehensive development and utilization of R.algida var.tangutica.

关 键 词：唐古特红景天 毒理作用 红景天苷 酪醇 抗缺氧 抗氧化 抗癌 抗衰老 

分 类 号：R285[医药卫生—中药学]