北京社区人群2型糖尿病血糖控制状态与牙周炎的相关性研究  

Correlation study on glycemic control and periodontitis in the Beijing community population with type 2 diabetes

作　　者：汤梓艳 王晓霞[3] 杨泓 徐筱[1] 刘雪娇 刘国景 郭园[2] 郭立新[3] 栾庆先[1] TANG Zi-yan;WANG Xiao-xia;YANG Hong;XU Xiao;LIU Xue-jiao;LIU Guo-jing;GUO Yuan;GUO Li-xin;LUAN Qing-xian(Department of Periodontology,Peking University School and Hospital of Stomatology,Beijing 100081,China)

机构地区：[1]北京大学口腔医学院·口腔医院牙周科、国家口腔医学中心、国家口腔疾病临床医学研究中心、口腔数字化医疗技术和材料国家工程实验室、口腔数字医学北京市重点实验室,北京100081 [2]北京大学口腔医学院·口腔医院口腔医院第二门诊部,北京100081 [3]北京医院·国家老年医学中心内分泌科

出　　处：《北京口腔医学》2023年第4期274-278,共5页Beijing Journal of Stomatology

基　　金：北京市自然科学基金(7222227)。

摘　　要：目的探讨北京城区2型糖尿病人群的血糖控制状态与牙周炎之间的相关性。方法本横断面研究,以北京城区7个社区的385名2型糖尿病常住居民为研究对象,调查内容包括问卷调查、体格检查、血生化检查、尿液检查及全口牙周检查。根据空腹血糖及糖化血红蛋白水平对研究对象进行血糖控制状态分组;根据AL≥3 mm%进行牙周炎分组,分析组间差异。以糖尿病血糖控制状态、牙周炎的二分组分别作为因变量,校正性别、年龄、收入、文化程度、BMI、吸烟、运动情况等混杂因素,二分类Logistic回归分析筛选可能的影响因素。结果血糖控制不良组重度牙周炎患者的占比显著高于控制良好组。校正混杂因素后,该2型糖尿病社区人群发生血糖控制不良的风险与AL≥4 mm%有关(OR=2.139,95%CI:1.049~4.362);患重度牙周炎的风险与空腹血糖有关(OR=1.153,95%CI:1.035~1.283)。结论在北京城区2型糖尿病人群中,糖尿病血糖控制状态与牙周炎严重程度显著相关。Objective To analyze the correlation between glycemic control and periodontitis in the Beijing community population with type 2 diabetes.Methods In this cross-sectional study,385 patients with type 2 diabetes from seven communities in Beijing were enrolled.They underwent questionnaire survey,physical examination,blood biochemical examination,urine examination,and periodontal examination.The glycemic control levels of the subjects were grouped according to fasting blood glucose and glycated hemoglobin,and the severity of periodontitis was grouped according to AL≥3mm%,and then the differences between groups were statistically compared.After adjusting for confounding factors such as gender,age,income,educational level,BMI,smoking,and physical activity,glycemic control and periodontal status were taken as the dependent variables in order to explore the possible influencing factors by binary Logistic regression analysis.Results The proportion of patients with severe periodontitis in poorly glycemic controlled group was significantly higher than that in well glycemic controlled group.After adjusting for confounding factors,the odds of poor glycemic control was associated with AL≥4mm%(OR=2.139,95%CI:1.049~4.362),and the odds of severe periodontitis was associated with fasting blood glucose(OR=1.153,95%CI:1.035~1.283).Conclusions There is a significant correlation between glycemic control and periodontitis in the Beijing community population with type 2 diabetes.

关 键 词：横断面研究 社区人群 血糖控制状态 牙周炎 

分 类 号：R587.2[医药卫生—内分泌] R781.42[医药卫生—内科学]