辅助生殖门诊中500例不孕症女性的病因分析探讨  

Etiological analysis of 500 cases of infertility in assisted reproduction clinic

作　　者：杨芸[1] 戴华[1] 王杜娟[1] Yang Yun;Dai Hua;Wang Dujuan(Department of Reproduction,Yancheng Maternal and Child Health Hospital,Yancheng 224000,China)

机构地区：[1]盐城市妇幼保健院生殖科,江苏盐城224000

出　　处：《实用妇科内分泌电子杂志》2023年第15期28-30,共3页Electronic Journal of Practical Gynecological Endocrinology

摘　　要：目的探讨辅助生殖门诊中500例不孕症女性的病因及影响因素。方法回顾性分析辅助生殖门诊接收的不孕症女性500例的临床资料。结果500例不孕症患者中,继发性不孕症208例,原发性不孕症292例。其中继发性不孕症患者中输卵管因素114例(54.81%),子宫与宫颈因素45例(21.63%),内分泌因素36例(17.31%),免疫因素11例(5.29%),不明原因2例(0.96%);原发性不孕症患者中输卵管因素62例(21.23%)、子宫与宫颈因素55例(18.84%),内分泌因素153例(52.40%),免疫因素17例(5.82%),不明原因5例(1.71%)。继发性不孕症患者内分泌因素与原发性不孕症比较,差异无统计学意义(P>0.05)。继发性不孕症与原发性不孕症患者的生殖道感染、子宫内膜异位症、术后损伤粘连发生情况对比,差异无统计学意义(P>0.05),发育异常情况比较差异具有统计学意义(P<0.05)。结论输卵管是导致女性继发性不孕症的首要因素,内分泌是导致女性原发性不孕症的首要因素,需要对其进行明确诊断,对症治疗,提高妊娠率。Objective To investigate the etiology and influencing factors of 500 cases of infertility in assisted reproduction clinic.Methods The clinical data of 500 cases of infertile women admitted to assisted reproduction clinic were retrospectively analyzed.Results Of the 500 infertility patients,208 were secondary infertility and 292 were primary infertility.Among the secondary infertility patients,there were 114 cases(54.81%)of tubal factors,45 cases(21.63%)of uterine and cervical factors,36 cases(17.31%)of endocrine factors,11 cases(5.29%)of immune factors,and 2 cases(0.96%)of unknown causes.There were 62 cases of tubal factors(21.23%),55 cases of uterine and cervical factors(18.84%),153 cases of endocrine factors(52.40%),17 cases of immune factors(5.82%),and 5 cases of unknown causes(1.71%).There was no significant difference in endocrine factors between secondary infertility patients and primary infertility(P>0.05).There was no significant difference in the incidence of reproductive tract infection,endometriosis and postoperative injury adhesion between secondary infertility and primary infertility patients(P>0.05),while there was significant difference in the incidence of developmental abnormalities(P<0.05).Conclusion Fallopian tube is the primary factor leading to female secondary infertility,endocrine is the primary factor leading to female primary infertility,it is necessary to make a clear diagnosis,symptomatic treatment,improve the pregnancy rate.

关 键 词：继发性不孕症 原发性不孕症 生殖道感染 

分 类 号：R711.6[医药卫生—妇产科学]