无创心输出量测量系统胸阻抗采集电路的设计  

Design of Chest Impedance Acquisition Circuit of Non-Invasive Cardiac Output Measurement System

作　　者：吴碧涛 李咏臻 黄海萍 石蓉 邓振进 Wu Bitao;Li Yongzhen;Huang Haiping;Shi Rong;Deng Zhenjin(Hunan Institute for Drug Control,Changsha Hunan 410001,China;School of Health Science and Engineering,University of Shanghai for Science and Technology,Shanghai 200093,China)

机构地区：[1]湖南省药品检验检测研究院,湖南长沙410001 [2]上海理工大学健康科学与工程学院,上海200093

出　　处：《医疗装备》2023年第17期32-36,共5页Medical Equipment

摘　　要：心输出量是临床血流动力学监测的重要指标。传统的Fickle法或热稀释法通过侵入性手段测量心输出量,存在风险和不适。而胸阻抗法基于心脏收缩和舒张时血液流动与胸腔阻抗的变化关系,可实现非侵入式、安全且可靠的心输出量测量。该研究以胸阻抗法、Nyboer的胸腔圆柱模型为理论基础,设计了以人体为基础阻抗,可测量心输出量的胸阻抗采集电路(包括恒流源电路、电压信号测量电路及50 Hz陷波电路),并利用Cadence软件对该电路进行了实验仿真,结果达到了预期设计目标。Cardiac output monitoring is a very important parameter index for clinical hemodynamic monitoring.The traditional Fickle method or thermodilution method usually requires invasive means to measure cardiac output,but there are risks and discomforts.The thoracic impedance method is based on the relationship between blood flow and thoracic impedance during cardiac contraction and relaxation,which can achieve non-invasive,safe and reliable cardiac output monitoring.In this research,a chest impedance acquisition circuit for cardiac output measurement is designed.Based on the chest impedance method,Nyboer's chest cylindrical model,the impedance changes before and after the blood flows into the aorta are detected based on the human body.The circuit mainly includes a constant current source circuit,a voltage signal measurement circuit and a 50 Hz notch circuit.Finally,the circuit is simulated and analyzed by Cadence software,and the test results achieve the expected design goals.The results of this study are of great significance for promoting the development of medical technology and the innovation of cardiac health monitoring,and provide strong support for improving patient care and promoting heart disease management.

关 键 词：心输出量 胸阻抗法 电路设计 实验仿真 

分 类 号：R197.39[医药卫生—卫生事业管理]