In phase with the nucleolus  

作　　者：Denis L.J.Lafontaine 

机构地区：[1]RNA Molecular Biology,Fonds de la Recherche Scientifque(FRS./FNRS),Universite libre de Brxelles(ULB),Biopark Campus,B-6041 Gosselies,Belgium

出　　处：《Cell Research》2023年第8期579-580,共2页细胞研究（英文版）

摘　　要：The nucleolus is a biomolecular condensate responsible for ribosome biogenesis.Using super-resolution microscopy,the team of Ling-Ling Chen has identified a novel nucleolar subcompartment,ascribing to it a function in processing the 3'ends of primary ribosomal RNA transcripts synthesized by RNA polymerase I.The nucleolus,a multilayered biomolecular condensate formed by liquid-liquid phase separation,is where the initial steps of ribosome biogenesis occur,alongwith other processes important forcell homeostasis.

关 键 词：PHASE STEPS SEPARATION 

分 类 号：Q2[生物学—细胞生物学]