基于三维斑点追踪成像评估左心室心肌应变对2型糖尿病患者发生主要不良心脏事件的预测  

Value of Left Ventricular Myocardial Strain Based on Three-dimensional Speckle Tracking Imaging in Predicting Major Adverse Cardiac Events in Patients with Type 2Diabetes Mellitus

作　　者：应康[1] 郭良云[1] 刘燕娜[1] 胡震[1] 曹婷 Ying Kang;Guo Liangyun;Liu Yanna;Hu Zhen;Cao Ting(Department of Ultrasound,the Second Affiliated Hospital of Nanchang University,Nanchang 330006,China;Department of Ultrasound,Gao’an People’s Hospital,Gao’an,Jiangxi 330800,China)

机构地区：[1]南昌大学第二附属医院超声科,南昌市330006 [2]高安市人民医院超声科,江西省高安市330800

出　　处：《中国超声医学杂志》2023年第8期883-886,共4页Chinese Journal of Ultrasound in Medicine

基　　金：江西省教育厅科学技术研究项目(No.170100)。

摘　　要：目的运用斑点追踪成像(STI)技术评估左室射血分数(LVEF)正常的2型糖尿病(T2DM)患者的左心室心肌应变,探索预测该类患者发生主要不良心脏事件(MACE)的最灵敏指标。方法选取249例LVEF正常的T2DM患者,中位随访时间24个月。依据随访期间是否发生MACE分为发生组和未发生组,分析STI测得的各项左心室应变参数。结果二维左心室整体长轴应变(2D-LVGLS)和三维左心室整体长轴应变(3D-LVGLS)是T2DM患者发生MACE的独立预测因子,受试者操作特征(ROC)曲线下面积分别为0.846、0.804,3D-LVGLS以-18.3%作为截断值预测发生MACE的灵敏度和特异度分别为81%和30%。结论3D-LVGLS是预测LVEF正常的T2DM患者发生MACE的最可靠指标;3D-LVGLS≥-18.3%可用来预测T2DM患者MACE的发生。Objective To investigate which strain indicator assessed by speckle tracking imaging technology was the most sensitive predictor of the development of major adverse cardiac events(MACE)for type 2diabetes mellitus(T2DM)patients with normal left ventricular ejection fraction(LVEF).Methods A total of 249T2DM patients with normal LVEF were selected and divided into MACE group and non-MACE group according to whether MACE occurred during the follow-up period.The median follow-up time was 24months.The left ventricular strain parameters measured by ultrasonic speckle tracking imaging were analyzed.Results Two-dimensional left ventricular global longitudinal strain and three-dimensional left ventricular global longitudinal strain(3D-LVGLS)were independent predictors of MACE in patients with T2DM,and the area under the receiver operating characteristic curve was 0.846and 0.804,respectively.The sensitivity and specificity of 3D-LVGLS in predicting MACE with-18.3%cut-off value were 81%and 30%,respectively.Conclusions 3D-LVGLS is the most reliable predictor for MACE in T2DM patients with normal LVEF.3D-LVGLS≥-18.3%can be used to predict the occurrence of MACE in T2DM patients.

关 键 词：斑点追踪成像技术 2型糖尿病 主要不良心脏事件 

分 类 号：R445.1[医药卫生—影像医学与核医学] R587.1[医药卫生—诊断学]