心内科质子泵抑制剂使用情况及合理性分析  

Analysis on the use and rationality of proton pump inhibitors in cardiology department

作　　者：姜彩云[1] 黄际薇[1] JIANG Cai-yun;HUANG Ji-wei(Department of Pharmacy,The Third Affiliated Hospital of Sun Yat-sen University,Guangzhou 510630,China)

机构地区：[1]中山大学附属第三医院药剂科,广州510630

出　　处：《中国处方药》2023年第9期70-72,共3页Journal of China Prescription Drug

基　　金：广东省医院药学研究基金-澳美基金(2021A14)。

摘　　要：目的分析心血管内科质子泵抑制剂(Proton Pump Inhibitors,PPIs)的使用情况,为质子泵抑制剂的规范应用提供参考。方法采用回顾性的调查方法,选取2020年7月~12月心血管内科病例作为分析对象,统计使用PPIs的具体情况。结果236例患者共使用了6个不同品种的PPIs药物,用药目的及占比分别为预防应激性溃疡94.07%、治疗性应用5.93%。用法主要为口服和静脉用药,用量多为每日1次。236例患者中有26例存在使用不合理情况,不合理率11.02%。不合理类型主要为无指征用药、用药频次不当。结论心内科住院患者使用PPIs以预防应激性溃疡为主要目的,使用泮托拉唑、雷贝拉唑为主。不合理用药情况中无指征用药较为突出,需加强培训,把握用药指征,以提高临床合理使用PPIs。Objective The use of proton pump inhibitors(PPIs)in cardiovascular medicine was analyzed to provide reference for the standard application of PPIs.Methods The retrospective investigation method was adopted,and the cases of cardiovascular medicine from June to December 2020 were selected as the analysis objects to make statistics on the specific situation of PPIs use.Results In 236 patients,a total of 6 different varieties of PPIs were used.The purpose and proportion of medication were to prevent stress ulcers(94.07%),and therapeutic applications(5.93%).It is mainly used orally and intravenously once a day.Among 236 patients,26 cases had irrational use,the irrational rate was 11.02%.The irrational types were mainly fingerless drug requisition and improper drug use frequency.Conclusion In the department of Cardiology,the main purpose of PPIs is to prevent stress ulcers,and pantoprazole and rabeprazole were used mainly.In irrational drug use,drug requisition without fingers is more prominent.Training should be strengthened to grasp the indications of drug use,so as to improve the rational use of PPIs in clinical practice.

关 键 词：质子泵抑制剂 合理性分析 使用情况 

分 类 号：R975[医药卫生—药品]